 Help support MIT OpenCourseWare by shopping at Amazon.com! MIT OpenCourseWare offers direct links to Amazon.com to purchase the books cited in this course. Click on the Amazon logo to the left of any citation and purchase the book from Amazon.com, and MIT OpenCourseWare will receive up to 10% of all purchases you make. Your support will enable MIT to continue offering open access to MIT courses. |
20.106J/1.084J: Systems Microbiology
Microbiology from a systems perspective.
Prerequisites
5.111, 5.112 or 3.091; 7.012, 7.013, or 7.014
Course Textbook
Madigan, Michael, and John Martinko. Brock Biology of Microorganisms. 11th ed. Upper Saddle River, NJ: Pearson Prentice Hall, 2005. ISBN: 9780131443297.
Grading
Grading criteria.
| ACTIVITIES |
PERCENTAGE |
| Problem Sets (~1 every 2 weeks) |
25% |
| Midterm I |
20% |
| Midterm II |
20% |
| Final Exam |
35% |
Calendar
Course calendar.
| Lec # |
TOPICS |
LECTURERS |
KEY DATES |
| 1 |
Early Earth/Microbial Evolution |
Prof. Ed DeLong |
|
| 2 |
Cell Structure/Function |
Prof. Ed DeLong |
Problem set 1 out |
| 3 |
Biological Energy Conservation |
Prof. Ed DeLong |
|
| 4 |
Microbial Growth |
Prof. David Schauer |
Problem set 1 due |
| 5 |
Metabolic Regulation |
Prof. Ed DeLong |
Problem set 2 out |
| 6 |
Virology |
Prof. David Schauer |
|
| 7 |
Information Flow in Biological Systems |
Prof. Ed DeLong |
Problem set 2 due |
|
Midterm I |
|
|
| 8 |
Regulation of Cell Activity |
Prof. Ed DeLong |
Problem set 3 out |
| 9 |
Genetic Exchange in Bacteria |
Prof. Ed DeLong |
|
| 10 |
Experimental Evolution: Optimization of Metabolic Systems |
Guest Lecturer, Prof. Christopher Marx from Harvard |
Problem set 3 due |
| 11 |
Genomics I |
Prof. Ed DeLong |
|
| 12 |
Genomics II |
Prof. Ed DeLong |
Problem set 4 out |
| 13 |
Metabolic Diversity I |
Prof. Ed DeLong |
|
| 14 |
Metabolic Diversity II |
Prof. Ed DeLong |
|
| 15 |
Microbial Ecology |
Prof. Ed DeLong |
Problem set 4 due |
|
Midterm II |
|
|
| 16 |
Microbial Growth Control |
Prof. David Schauer |
Problem set 5 out |
| 17 |
Microbe-host Interactions |
Prof. David Schauer |
|
| 18 |
Immunology I |
Megan McBee |
|
| 19 |
Immunology II |
Megan McBee |
Problem set 5 due |
| 20 |
Diagnostic Microbiology |
Prof. David Schauer |
Problem set 6 out |
| 21 |
Person-to-person Transmission |
Prof. David Schauer |
|
| 22 |
Epidemiology |
Megan McBee |
Problem set 6 due |
| 23 |
Animal- and Arthropod-transmitted Diseases |
Prof. David Schauer |
|
| 24 |
Review |
Prof. David Schauer |
|
|
Final Exam |
|
|