The calendar below provides information on the course's lecture (L) and recitation (R) sessions.
DAL: Prof. Douglas Lauffenburger
FMW: Prof. Forest White
KA: Kathyryn Armstrong
SW: Shan Wu
CR: Craig Rothman
Course calendar.
| SES # |
INSTRUCTORS |
TOPICS |
KEY DATES |
| L1 |
FMW |
Introduction - 20, 20.320, Biology, Mechanisms, and Modeling Protein Interactions |
|
| R1 |
KA/SW/CR |
Recitation 1 |
|
| L2 |
FMW |
Protein Interactions II
Thermodynamics of Monovalent Interactions |
Problem set 1 assigned |
| L3 |
FMW |
Monovalent Interactions |
|
| R2 |
|
Recitation 2 |
|
| L4 |
FMW |
Fractional Saturation |
Problem set 1 due
Problem set 2 assigned |
| L5 |
FMW |
Measurement Techniques for Kd |
|
| R3 |
KA/SW/CR |
Recitation 3 |
|
| L6 |
FMW |
Perturbations to Monovalent Interactions |
Problem set 2 due
Problem set 3 assigned |
| L7 |
FMW |
Perturbations II - Solution Effects |
|
| R4 |
|
Recitation 4 |
|
| L8 |
FMW |
Multivalent Binding |
Problem set 3 due
Problem set 4 assigned |
| L9 |
FMW |
Cooperativity |
|
| R5 |
|
Recitation 5 |
|
| L10 |
FMW |
Avidity and Effective Concentration |
Problem set 4 due |
| R6 |
CR/SW |
Recitation 6 |
|
|
FMW |
Exam 1 - Monovalent Binding, Measurement, Perturbations, Multivalent Binding, Cooperativity |
|
| L11 |
FMW |
Enzyme Kinetics I |
|
| L12 |
FMW |
Enzyme Kinetics II |
|
| R7 |
|
Recitation 7 |
|
| R8 |
|
Recitation 8 |
|
| L13 |
DAL |
Enzyme Inhibitors |
Problem set 5 assigned |
| L14 |
DAL |
Integrating Pathways Into Networks |
|
| R9 |
|
Recitation 9 |
|
| L15 |
DAL |
Ligand-Receptor Interactions |
Problem set 5 due
Problem set 6 assigned |
| L16 |
DAL |
Endocytic Trafficking I |
|
| R10 |
|
Recitation 10 |
|
| R11 |
CR/SW |
Recitation 11 |
Problem set 6 due |
|
DAL/FMW |
Exam 2 - Avidity, Enzymes, and Networks |
|
| L17 |
DAL |
Endocytic Trafficking II |
Problem set 7 assigned |
| L18 |
DAL |
Biomolecular Reactions in Context of Transport |
|
| R12 |
|
Recitation 12 |
|
| L19 |
DAL |
Fundamentals of Molecular Transport |
Problem set 7 due
Problem set 8 assigned |
| L20 |
DAL |
Reaction Terms and Approximations |
|
| R13 |
|
Recitation 13 |
|
| L21 |
DAL |
Macroscopic and Microscopic Effects of Diffusion |
Problem set 8 due
Problem set 9 assigned (ungraded) |
| L22 |
DAL |
Autocrine/Paracrine Cell-cell Communication |
|
| R14 |
|
Recitation 14 |
|
| L23 |
DAL |
Cell Population Dynamics I: Cell Growth, Death, Differentiation, and Product Synthesis |
|
| L24 |
DAL |
Cell Population Dynamics II: Application to Tissues and Bioreactors |
|
|
DAL |
Exam 3 - Test Accumulated Knowledge (Emphasis on Mechanisms Underlying Biomolecular Systems) |
|