Syllabus

Description

The intention of the course is to develop a broad skill set for research in biomedical optics including the fundamentals of light-tissue interaction, technologies such as microscopy, lasers and fiber optics and issues related to animal and human research. The lecture series will also introduce current clinical and basic biology challenges that may be addressed by optical solutions. The students will prepare a report summarizing the critical issues of selected challenges and will propose technical solutions.

Recommended Texts

Hecht, Eugene. Optics. Boston, MA: Addison-Wesley Longman, Inc., 2001.

Saleh, Bahaa, and Malvin Teich. Fundamentals of Photonics. Hoboken, NJ: Wiley & Sons, 1991.

Siegman, Anthony. Lasers. Sausalito, CA: University Science Books, 1986.

Grading Policy


ACTIVITIES PERCENTAGES
Class Participation 20%
Two Reports 40% each

Calendar


LEC # TOPICS INSTRUCTORS KEY DATES
1 Introduction Brett E. Bouma
2 Basics of Optics I Brett E. Bouma
3 Basics of Optics II Brett E. Bouma
4 Basics of Optics III Brett E. Bouma
5 Basics of Optics IV Brett E. Bouma
6 Light Propagation in Tissue Brett E. Bouma
7 Propagation Modelling Brett E. Bouma
8 Optical Components Brett E. Bouma
9 Anatomy/Pathology I Guillermo J. Tearney
10 Wellman Center Lab Tour Mid-Term paper due
11 Optical Coherence Tomography I Guest
12 Optical Coherence Tomography II Guest
13 Anatomy/Pathology II Guillermo J. Tearney
14 Cells/Histopathology and Microscopic Scattering Guillermo J. Tearney
15 Cells/Histopathology and Microscopic Scattering II Guillermo J. Tearney
16 Macroscopic Tissue Optics I Guillermo J. Tearney
17 Macroscopic Tissue Optics II Guillermo J. Tearney
18 Microscopy Guillermo J. Tearney
19 Confocal/Endoscopic Confocal Guillermo J. Tearney
20 Two-photon Microscopy Guest
21 Polarization in Tissue Johannes F. de Boer
22 Optics in Ophthalmology Johannes F. de Boer
23 Absorption, Diffuse Reflection, Light Scattering Spectroscopy Johannes F. de Boer
24 Raman, Fluorescence Lifetime Imaging Johannes F. de Boer
25 Photo-acoustic Imaging Johannes F. de Boer
26 Speckle and Weak Localization Johannes F. de Boer Final paper due