Special software is required to use some of the files in this section: .mov.

Lectures: 1 | 2 | 3 | 4-5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 16 | 17 | 19 | 20 | 21 | 22 | 23 | 26

Molecular Motors

1. Molecular Motors:
   • Kinesin Structure
   • Dyenin and Kinesin Move in Opposite Directions along Microtubules
   • Myosin Moves on Action Filaments
   • Animation of Motion of Kinesin on a Microtubule (MOV)
2. General Scheme of Motor Transport with the Consumption of ATP (Page 1 (GIF) of Lecture Notes)
3. Motion in a Noisy Environment:

Motion in a noisy environment.

• Feynman's Ratchet and Pawl
• Simulation of a Brownian Motor
• From the Web page of George Oster:
  • Wang, H., and G. Oster. "Ratchets, Power Strokes, and Molecular Motors." Appl. Phys. A 75, no. 315 (2002). (PDF)
  • Bustamante, C., D. Keller, and G. Oster. "The Physics of Molecular Motors." Acc. Chem. Res. 34, no. 412 (2001). (PDF)
  • Animation of Energy Landscape for a Rotary Motor (MOV)

1. Asymmetric Hopping Models:
   • Fisher, M. E., and A. B. Kolomeisky. "The Force Exerted by a Molecular Motor." PNAS 96, no. 6597 (1999).
   • Multiple Internal States
   • Solution with One Internal State (Page 2 (GIF) of Lecture Notes)
   • Einstein Force, Stalling Force (Page 3 (GIF) of Lecture Notes)
2. Capturing and Viewing Single Molecules:
   • Optical Tweezers
   • Fluorescent Light Microscopy
   • Actin-myosin Movies by Albrecht Ott
3. Theory of Brownian Motion (Lecture Notes (PDF))

Some Related Links

• Kinesin HomePage
• Kinesin Motors - the Movies
• Mechanical properties of kinesin (by Sylvia Jeney)
• Dyenin and HIV
• Movie of in Vitro Microtubule Gliding (MOV)
• MIT Course 3.052 Internet Resources
• Lecture at Delft by Gerrit E. W. Bauer (PDF)