Lectures: 1 | 2 | 3 | 4-5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 16 | 17 | 19 | 20 | 21 | 22 | 23 | 26

Biomolecular Forces and Energies

1. Quick Look at Structures of Biomolecules:
   • Small Molecules: Water and Sugars
   • Nucleic Acids: DNA, RNA
   • Polypeptides and Proteins
2. Review of Molecular Forces
3. Chemical Forces:
   • Covalent
     • 1 Bond: Vibrational
     • 2 Bonds: Rotational
     • 3 Bonds: Torsional
   • Non-covalent
     • Electrostatic
     • Van der Waals
     • Hydrogen Bond
4. EntropyAndentropic>=Forces<=:
   • Entropy of Mixing
   • Hydrophobic Effect

Recommended Reading

Protein Physics, Alexei V. Finkelstein and Oleg B. Ptitsyn (Chapters 1-6)

Protein Viewers

• RASMOL (For Mac OS X Distribution )
• MDL Chime: Downloading Instructions
• Protein Explorer