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Video Clips

RealVideo®
6:05 minutes (21:23 - 27:28)
Life cycle of viruses with different types of genomes. Some viruses containing RNA genomes use reverse transcriptase to make DNA from RNA. Example: HIV.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
DNA replication and transcription
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RealVideo®
13:30 minutes (2:20 - 15:50)
Life cycle and infection of the polio virus. Jenner and his discovery of vaccine for polio. Vaccines can be made from heat attenuated or formaldehyde treated polio viruses.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Viral life cycle
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RealVideo®
34:25 minutes (15:38 - 50:03)
History of AIDS, discovery of HIV, life cycle, infection, and inhibitors of HIV.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
None
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RealVideo®
9:14 minutes (5:44 - 14:58)
Structure and mechanism of replication of RNA viruses that synthesize RNA from RNA template. Example: Tobacco mosaic virus. Structure and integration of retroviruses that use reverse transcriptase to make DNA from RNA template. Example: HIV.
Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke
None
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RealVideo®
6:28 minutes (17:54 - 24:22)
Structure, infection, and life cycle of bacterial virus. Plaque formation upon infection.
Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke
None
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Lecture Notes

PDF
All pages
Structure, life cycle, and examples of all types of viruses classified by their genomes. Clear and detailed summary of virology.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
None
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PDF
All pages
Comprehensive review of the structure, life cycle, and infection of the human immunodeficiency virus.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Use with AIDS sections
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Practice Problems

PDF
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Problem 1
Immune response to viral infections and how viruses try to evade the system.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
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PDF
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Problem 4
Various viral genomes and incorporation into the host genome.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Restriction enzymes and gel electrophoresis
Solution (PDF)#
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PDF
Problem 4I (page 4)
Order of events occurring through the life cycle of HIV.
Prof. Tyler Jacks, Prof. Hazel Sive
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PDF
Problem 4III-4V (page 5)
Potential drug targets in the HIV life cycle.
Prof. Tyler Jacks, Prof. Hazel Sive
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PDF
Problem 1B (page 3)
HIV life cycle, reverse transcriptase, integrase, and drugs that prevent HIV reproduction.
Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke
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Exam Questions

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Problem 5 (page 8)
Structure and life cycle of viruses. Viral infections and potential to cause AIDS and cancer.
Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
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