Evidence of evolution from comparison of various yeast genomes. Essential genes and promoters are better conserved over time. Co-expression and co-conservation can help determine the function of unknown genes or regulatory sequences. Genomic comparison to human and other mammals.

Evolutionary trees based on DNA or RNA sequences - mutations and divergence. Sequences that are non-essential contain more variation/neutral mutations.

Mapping humans based on genetic diversity. Support for Out-of-Africa theory for and human movement through time.

Discussion of the history and evidence of life on Earth. Evolution of three early lineages.