Readings

The table below provides information on the course's lecture (L) and exam (E) sessions.

Text Readings

All Text Readings are in Dill, K., and S. Bromberg. Molecular Driving Forces. New York, NY: Routledge, 2002. ISBN: 9780815320517.

Additional References

van Holde = van Holde, K. E., W. C. Johnson, and P. S. Ho. Principles of Physical Biochemistry. Upper Saddle River, NJ: Prentice Hall, 1998. ISBN: 9780137204595.

Eisenberg = Eisenberg, D., and D. Crothers. Physical Chemistry with Applications to the Life Sciences. Menlo Park, CA: Benjamin/Cummings, 1979. ISBN: 9780805324020.

Kittel = Kittel, C., and H. Kroemer. Thermal Physics. 2nd ed. New York, NY: W.H. Freeman, 1980. ISBN: 9780716710882.

SES #	TOPICS	TEXT READINGS	ADDITIONAL REFERENCES
L1	Introduction Purpose of Stat Mech Probability	Ch. 1 (Ex. 1.1-1.6)
L2	Probability	Ch. 1, 2
L3	Equilibrium States	Ch. 2 (Through Ex. 2.2)
L4	Equilibrium States – Lattice Model for Diffusion Rubber Elasticity	Ch. 2
L5	Introduction to Conservation Laws (1st Law, Quantization, 2nd Law)	Ch. 3
L6	Boltzmann’s Law and Entropy as an Extensive Property Law of Increased Entropy	Ch. 6 (Through Ex. 6.2)	Kittel, Ch. 2
L7	More Boltzmann’s Law Partition Functions	Ch. 6
L8	Simulations PCR
E1	Quiz I
L9	Thermodynamic Systems Intensive/Extensive Properties Fundamental Equations for Energy and Entropy Definitions of Thermodynamic Driving Forces (Part 1) Thermodynamic Forces Homogeneous Functions Definition of Equilibrium, Temperature, Pressure	Ch. 7 (To Ex. 7.4)
L10	Introduction to Chemical Potential - Thermo Cycles - First Law Relations between Heat, Work, Energy	Ch. 7
L11	Reversible and Irreversible Processes	Ch. 7
L12	Introduction to Free Energy Helmholtz Free energy	Ch. 8
L13	Enthalpy Gibbs Free Energy	Ch. 8	Kittel Problem, 9.4 van Holde, Ch. 2
L14	Fundamental Equations and their Natural Variables Heat Capacities Equilibrium Temperature	Ch. 8
L15	Thermodynamic Cycles Carnot Cycle and Inequality Heat Engines Path Dependence	Ch. 8	Kittel, Ch. 8
L16	Partial Molar Properties	Ch. 9
L17	Partial Molar Properties II	Ch. 9	Eisenberg, Ch. 7
L18	Simulations Monte Carlo
E2	Quiz II
L19	Boltzmann Distribution Law	Ch. 10
L20	Partition Functions	Ch. 10
L21	Prediction of Thermodynamic Properties from Partition Functions Ensembles	Ch. 10	Eisenberg, Ch. 14
L22	Quantum Partition Function	Ch. 10, 11
L23	Equipartition	Ch. 11
L24	Equipartition (cont.)	Ch. 11
L25	Chemical Equlibria Le Chatelier’s Principle (Ex. 8, Pressure Denaturation of Proteins) van’t Hoff	Ch. 13 (To Ex. 13.18)	van Holde, Ch. 3
L26	Solid-liquid-gas Equilibrium	Ch. 14
L27	Solutions and Mixtures Polymers	Ch. 15, 31
L28	Solvation – Osmotic Pressure	Ch. 16
L29	Solvation – Protein/Macromolecule Adsorption at Interfaces	Ch. 16	van Holde, Ch. 2
L30	Polymer Chain	Ch. 31
E3	Quiz III
L31	Polymer Chain II	Ch. 32
L32	Polymer Chain III	Ch. 33
L33	Cooperativity	Ch. 26
L34	Cooperativity (cont.)	Ch. 28
L35	Protein Folding		van Holde, Ch. 2
L36	Review

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