BioBuilder® is a resource for hands-on activities and informative animations on synthetic biology, and a place to discuss the challenge of engineering biological systems. http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations 2013-01-25T05:50:53+05:00 MIT OpenCourseWare http://ocw.mit.edu en-US Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>It&rsquo;s not easy being green. It&rsquo;s also not easy to figure out why Buddy is green, but Sally explains how open reading frames help.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/1.-open-reading-frames-orfs/MIT20_020S09_01_orf.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/1.-open-reading-frames-orfs/MIT20_020S09_01_orf.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_orf.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/1N6Wvz-6FNI>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/1.-open-reading-frames-orfs Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Not all apps are created equal. Dude gets lessoned on how to build a gene using the correct parts in the correct order.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/2.-building-a-gene-correct-parts-in-correct-order/MIT20_020S09_02_abg.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/2.-building-a-gene-correct-parts-in-correct-order/MIT20_020S09_02_abg.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_abg.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/MvXC1dUDxkg>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/2.-building-a-gene-correct-parts-in-correct-order Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p><span dir="ltr">Dude cops an attitude. If we know the parts of a biological system, why can't we design them to snap together like pieces from a model robot kit? </span></p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/3.-genetic-programs-why-parts-don2019t-simply-snap-together/MIT20_020S09_03_parts.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/3.-genetic-programs-why-parts-don2019t-simply-snap-together/MIT20_020S09_03_parts.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_parts.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/o1bk4otKZw8>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/3.-genetic-programs-why-parts-don2019t-simply-snap-together Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Buddy&rsquo;s growth is out of control. Sally shows Dude how the right device can be used as an on-off switch to keep Buddy from blowing up.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/4.-genetic-digital-devices-the-on-off-switch/MIT20_020S09_04_genetic.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/4.-genetic-digital-devices-the-on-off-switch/MIT20_020S09_04_genetic.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_genetic.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/LRcYRm5daCU>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/4.-genetic-digital-devices-the-on-off-switch Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p><a href="http://ung.igem.org/">iGEM</a> team member Izzy tells Dude how her team&rsquo;s project to detect arsenic in well water used the process of abstraction.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/5.-the-abstraction-process-arsenic-detector/MIT20_020S09_05_abstraction.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/5.-the-abstraction-process-arsenic-detector/MIT20_020S09_05_abstraction.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_abstraction.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/gTtZrPy_SzQ>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/5.-the-abstraction-process-arsenic-detector Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Green light, go. Red light, stop. A transcriptional inverter may not work as fast as a traffic light, but Izzy helps Dude understand how this type of device can help him solve Buddy&rsquo;s overgrowth.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/6.-controlling-growth-the-transcriptional-inverter/MIT20_020S09_06_inverter.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/6.-controlling-growth-the-transcriptional-inverter/MIT20_020S09_06_inverter.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_inverter.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/6a2YKft1ZxQ>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/6.-controlling-growth-the-transcriptional-inverter Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Order up! Dude is ready to string together his DNA design, but doesn&rsquo;t know how.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/7.-dna-synthesis-stringing-parts-together/MIT20_020S09_07_dna-v2.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/7.-dna-synthesis-stringing-parts-together/MIT20_020S09_07_dna.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_dna.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/mXkOYxyChfg>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/7.-dna-synthesis-stringing-parts-together Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Izzy discusses what measurement data is available for biological parts, and Sally gives an overview of scientific measurements.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/8.-measurement-for-biological-parts/MIT20_020S09_08_measurement.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/8.-measurement-for-biological-parts/MIT20_020S09_08_measurement.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_measurement.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/XTUe-VMvRis>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/8.-measurement-for-biological-parts Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Dude&rsquo;s got the <a target="_blank" href="http://ung.igem.org/">iGEM</a> competition in the bag. At least that&rsquo;s what he thinks.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/9.-the-igem-competition/MIT20_020S09_09_igem.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/9.-the-igem-competition/MIT20_020S09_09_igem.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_igem.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/bJFqcqQcybg>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/9.-the-igem-competition Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Dude&rsquo;s plan to make viral cocoa beans using a BL4 virus gets Sally&rsquo;s attention fast. Time to school Dude on the biosafety issues of synthetic biology.</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/10.-biosafety-levels/MIT20_020S09_10_bsl.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/10.-biosafety-levels/MIT20_020S09_10_bsl.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_bsl.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/uyNj56g5rHY>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/10.-biosafety-levels Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm <p>Izzy and Sally help Dude keep up with the cells growing in the lab. This video looks at the stages of bacterial cell growth, how to measure them, and launches the BioBuilder activity #1: Eau That Smell!</p>Subtitles: <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/11.-cell-growth-and-division/MIT20_020S09_11_bioprimer.srt>SRT (English - US)</a><br>Thumbnail - <a href= /courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/11.-cell-growth-and-division/MIT20_020S09_11_bioprimer.jpg>JPG (OCW)</a><br>Video - download: <a href= http://www.archive.org/download/MIT20_020S09/MIT20_020S09_bioprimer.mp4>Internet Archive (MP4)</a><br>Video - stream: <a href= http://www.youtube.com/v/CUrlh0yrQ8s>YouTube </a><br><br><a href= 'http://ocw.mit.edu/terms/'>(CC BY-NC-SA)</a><br><br> http://ocw.mit.edu/courses/biological-engineering/20-020-introduction-to-biological-engineering-design-spring-2009/biobuilder-animations/11.-cell-growth-and-division Kuldell, Natalie Endy, Andrew 2009-12-22T07:36:40+05:00 en-US MIT OpenCourseWare http://ocw.mit.edu Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm