Lecture Notes

PCD = Prof. Peter Dedon
SRT = Prof. Steven Tannenbaum

LEC # TOPICS LECTURERS
1 Introduction and Principles (PDF) PCD
2 Chemistry/Biochemistry Review  
3 Overview of Drug Development Guest: Dr. Robert Rubin
4 Uptake/Transport/Distribution of Drugs (PDF) PCD
5 Drug Transporters Guest: Dr. Keith Hoffmaster
6 Bioethics Seminar  
7 Drug Transporters (cont.) Guest: Dr. Keith Hoffmaster
8 Introduction to Drug Metabolism SRT
9 Liver Lecture (PDF)  
10 Drug Metabolism 2 SRT
11 Drug Metabolism 3 Guest: Dr. Sean Harriman
12 Drug Metabolism 4 Guest: Dr. Sean Harriman
13 Quiz Review  
  Quiz 1 SRT
14 Oxygen Radicals in Drug Toxicity SRT
15 Drug Toxicities SRT
16 Drug Toxicities (cont.) SRT
17 Bioethics Seminar  
18 Pharmacokinetics (PDF) PCD
19 Pharmacokinetics (cont.) (PDF) PCD
20 Receptors and Case Study - Omeprazole (PDF) PCD
21 Case Study - Omeprazole (PDF) PCD
22 Case Study - Omeprazole (cont.) (PDF) PCD
23 Case Study - Acetaminophen SRT
24 Case Study - Acetaminophen (cont.) SRT
25 Case Study - Statins SRT/PCD
26 Case Study - Statins (cont.) SRT/PCD
27 Drug Industry Seminar Guest: Mark Trusheim (Massachusetts Biotech Council)
28 Case Study - Statins (cont.) SRT/PCD
29 Student Presentations  
30 Quiz Review  
31 Student Presentations (cont.)  
  Quiz 2