Prof. Peter Dedon
Prof. Steven Tannenbaum
Dr. Mark Murcko
Dr. Charles Knutson
This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets.
Dedon, Peter, Steven Tannenbaum, Mark Murcko, and Charles Knutson. 20.201 Mechanisms of Drug Actions, Fall 2013. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/biological-engineering/20-201-mechanisms-of-drug-actions-fall-2013 (Accessed). License: Creative Commons BY-NC-SA