Biomolecular Kinetics and Cell Dynamics

As taught in: Spring 2006

Michaelis-Menten plot.

This plot of velocity vs. substrate concentration is based on the Michaelis-Menten equation. The Michaelis-Menten constant, KM, is the substrate concentration at which the enzyme reaction proceeds at half the maximum velocity. (Figure by MIT OpenCourseWare.)

Instructors:

Prof. Douglas Lauffenburger

Prof. Forest White

MIT Course Number:

20.320

Level:

Undergraduate

Course Features

Course Description

This class covers analysis of kinetics and dynamics of molecular and cellular processes across a hierarchy of scales, including intracellular, extracellular, and cell population levels; a spectrum of biotechnology applications are also taken into consideration. Topics include gene regulation networks; nucleic acid hybridization; signal transduction pathways; and cell populations in tissues and bioreactors. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.