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This plot of velocity vs. substrate concentration is based on the Michaelis-Menten equation. The Michaelis-Menten constant, KM, is the substrate concentration at which the enzyme reaction proceeds at half the maximum velocity. (Figure by MIT OpenCourseWare.)
Prof. Douglas Lauffenburger
Prof. Forest White
20.320
Spring 2006
Undergraduate
This class covers analysis of kinetics and dynamics of molecular and cellular processes across a hierarchy of scales, including intracellular, extracellular, and cell population levels; a spectrum of biotechnology applications are also taken into consideration. Topics include gene regulation networks; nucleic acid hybridization; signal transduction pathways; and cell populations in tissues and bioreactors. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.
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