Principles of Human Disease

As taught in: Spring 2006

Illustration of a gene undergoing gene therapy.

Gene therapy using an adenovirus vector. Image courtesy of the U.S. National Library of Medicine.

Instructors:

Prof. David Housman

Prof. Jacqueline Lees

MIT Course Number:

7.27

Level:

Undergraduate

Course Description

This course covers current understanding of, and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Topics include: The Genetics of Simple and Complex Traits; Karyotypic Analysis and Positional Cloning; Genetic Diagnosis; The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression, and Treatment; The Interaction between Genetics and Environment; Animal Models of Human Disease; Cancer; and Conventional and Gene Therapy Treatment Strategies.