Network Medicine: Using Systems Biology and Signaling Networks to Create Novel Cancer Therapeutics

a network diagram made up of dots and lines, representing the interactions between proteins in a yeast cell.

Representation of complex systems as networks can be useful for visualizing their underlying structure, identifying functional units, and informing new hypotheses. The network diagram shown here represents a map of protein-protein interactions in a yeast (Saccharomyces cerevisiae) cell (Image by Hawoong Jeong, KAIST, Korea).


MIT Course Number


As Taught In

Fall 2012



Cite This Course

Course Description

In this course, we will survey the primary systems biology literature, particularly as it pertains to understanding and treating various forms of cancer. We will consider various computational and experimental techniques being used in the field of systems biology, focusing on how systems principles have helped advance biological understanding. We will also discuss the application of the principles of systems biology and network biology to drug development, an emerging discipline called "network medicine."

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Michael Lee. 7.343 Network Medicine: Using Systems Biology and Signaling Networks to Create Novel Cancer Therapeutics, Fall 2012. (Massachusetts Institute of Technology: MIT OpenCourseWare), (Accessed). License: Creative Commons BY-NC-SA

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