Prof. David Gifford
Prof. Tommi Jaakkola
7.90J / 6.874J
The course focuses on casting contemporary problems in systems biology and functional genomics in computational terms and providing appropriate tools and methods to solve them. Topics include genome structure and function, transcriptional regulation, and stem cell biology in particular; measurement technologies such as microarrays (expression, protein-DNA interactions, chromatin structure); statistical data analysis, predictive and causal inference, and experiment design. The emphasis is on coupling problem structures (biological questions) with appropriate computational approaches.
Gifford, David, and Tommi Jaakkola. 7.90J Computational Functional Genomics, Spring 2005. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/biology/7-90j-computational-functional-genomics-spring-2005 (Accessed). License: Creative Commons BY-NC-SA