Biochemistry and Pharmacology of Synaptic Transmission

The neurotransmitter serotonin.

Image of the neurotransmitter serotonin. (Image courtesy of MIT's Department of Brain and Cognitive Sciences.)

Instructor(s)

MIT Course Number

9.15 / 9.150

As Taught In

Fall 2007

Level

Undergraduate / Graduate

Translated Versions

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Course Description

This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. We focus on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); we also examine amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems and ion fluxes that they control. The involvement of particular neurotransmitters in human diseases is considered.

Wurtman, Richard. 9.15 Biochemistry and Pharmacology of Synaptic Transmission, Fall 2007. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/brain-and-cognitive-sciences/9-15-biochemistry-and-pharmacology-of-synaptic-transmission-fall-2007 (Accessed). License: Creative Commons BY-NC-SA


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