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Readings

Required Text

[S&K] Amazon logo Shuler, Michael L., and Fikret Kargi. Bioprocess Engineering: Basic Concepts. 2nd ed. Upper Saddle River, NJ: Prentice Hall PTR, 2001. ISBN: 9780130819086.

Additional Resources

Amazon logo Blanch, Harvey W., and D. S. Clark, eds. Biochemical Engineering. New York, NY: Marcel Dekker Incorporated, 1997. ISBN: 9780824700997.

Amazon logo Bailey, James E., and David F. Ollis. Biochemical Engineering Fundamentals. New York, NY: McGraw-Hill Education, 1986. ISBN: 9780070666016.

Rozzell, J. D. "Commercial scale biocatalysis: myths and realities." Bioorg Med Chem 7, no. 10 (October 1999): 2253-61.

SES # TOPICS READINGS
1 Course Overview, Enzyme Classification S&K. Chapter 1.
2 Enzyme Kinetics (Single-substrate Reactions), Measurement S&K. Chapter 3.1-3.3.3.
3 Enzyme Inhibition S&K. Chapter 3.3.4.
4 Enzyme Inhibition, pH and Temp Effects S&K. Chapter 3.3.5.
5 Non-ideal Enzyme Kinetics Class notes
6 Immobilized Enzyme Kinetics - External S&K. Chapter 3.4.
7 Immobilized Enzyme Kinetics - Internal S&K. Chapter 3.4.
8 Applications of Enzyme Catalysis (Biocatalysis) S&K. Chapter 3.5, 3.6.

Handouts
9 Microbial Growth S&K. Chapter 6.1-6.2.
10 Microbial Growth - Batch Cultivation Profiles S&K. Chapter 6.1-6.2.
11 Stoichiometry of Growth, Product Formation S&K. Chapter 7.
12 Stoichiometry of Growth, Product Formation (cont.) S&K. Chapter 7.
13 Models of Microbial Growth S&K. Chapter 6.3.
14 Models of Microbial Growth (cont.) S&K. Chapter 6.3.
15 Continuous Culture S&K. Chapter 6.4.
16 Continuous Culture (cont.) S&K. Chapter 6.4.
17 Bioreactor Design S&K. Chapter 9.1-9.3.
18 Bioreactor Design (cont.) S&K. Chapter 9.1-9.3.
19 Bioreactor Design (cont.)
20 Mass Transfer S&K. Chapter 6.2.3-6.2.4, 10.2.3.
21 Mass Transfer (cont.) S&K. Chapter 6.2.3-6.2.4, 10.2.3.
22 Heat Transfer, Media and Air Sterilization S&K. Chapter 10.4.
23 Scale-up S&K. Chapter 10.2.4.
24 Scale-down S&K. Chapter 10.2.5.
25 Animal Cell Culture S&K. Chapter 12.
26 Animal Cell Culture (cont.) S&K. Chapter 12.
27 Mixed Cultures S&K. Chapter 16.
28 Mixed Cultures (cont.) S&K. Chapter 16.
29 Medium Development Handouts
30 Medium Development (cont.) Handouts
31 Cellular Engineering - An Engineer's View Towards Recombinant Organisms S&K. Chapter 14.

Handouts
32 Cellular Engineering/Molecular Biology for Process Engineering S&K. Chapter 14.

Handouts
33 Cellular Engineering/Molecular Biology for Process Engineering (cont.) S&K. Chapter 14.

Handouts
34 Enzyme Engineering for Process Improvement Handouts
35 Enzyme Engineering for Process Improvement (cont.) Handouts