Course Description
This course covers the following topics: X-ray diffraction: symmetry, space groups, geometry of diffraction, structure factors, phase problem, direct methods, Patterson methods, electron density maps, structure refinement, how to grow good crystals, powder methods, limits of X-ray diffraction methods, and structure …
This course covers the following topics: X-ray diffraction: symmetry, space groups, geometry of diffraction, structure factors, phase problem, direct methods, Patterson methods, electron density maps, structure refinement, how to grow good crystals, powder methods, limits of X-ray diffraction methods, and structure data bases.
Course Info
Instructor
Departments
Learning Resource Types
notes
Lecture Notes
![Molecular model of amino acid tyrosine overlaid on photograph of xray diffractometer.](/courses/5-069-crystal-structure-analysis-spring-2010/554135c46af1873203e11f6560f42e7c_5-069s10.jpg)
Molecular model of the amino acid tyrosine with experimental electron density in front of an X-ray diffractometer at MIT. The tyrosine is part of the crystal structure of phosphoglycerate mutase from M. tuberculosis. See Mueller, P., et al. Acta Cryst D61 (2005): 309-315. (Figure and photograph by Dr. Peter Mueller.)