Molecular Biology and Genetics in Modern Medicine

Pedigrees showing two approaches for collecting families for linkage analysis.

Diagram of two approaches for collecting families for a linkage analysis. Top (A): part of a Huntington's disease analysis from a single large pedigree. Bottom (B): cystic fibrosis linkage in a collection of many smaller families.  See notes for Lecture 3. (Figure by MIT OpenCourseWare.)

Instructor(s)

MIT Course Number

HST.161

As Taught In

Fall 2007

Level

Graduate

Cite This Course

Course Description

This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics.

Housman, David, and Anne Giersch. HST.161 Molecular Biology and Genetics in Modern Medicine, Fall 2007. (MIT OpenCourseWare: Massachusetts Institute of Technology), http://ocw.mit.edu/courses/health-sciences-and-technology/hst-161-molecular-biology-and-genetics-in-modern-medicine-fall-2007 (Accessed). License: Creative Commons BY-NC-SA


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