HST.176 | Fall 2005 | Graduate

Cellular and Molecular Immunology

Readings

Required Readings

Abbas, Abul K., and Andrew Lichtman. Cellular and Molecular Immunology. 6th ed. Philadelphia, PA: Saunders, 2005. ISBN: 9781416023890.

 Rosen, Fred, and Raif Geha. Case Studies in Immunology: A Clinical Companion. 4th ed. New York, NY: Garland Pub., 2004. ISBN: 9780815341024. (Paperback)

 Janeway, Charles A., et al. Immunobiology: The Immune System in Health and Disease. New York, NY: Garland Science, 2004. ISBN: 9780443073106 .

 DeGowin, Richard L., and Donald D. Brown. DeGowin’s Diagnostic Examination. New York, NY: McGraw-Hill, Health Professions Division, 1999. ISBN: 9780070164437.

 Kasper, Dennis L., Eugene Braunwald, Anthony Fauci, Stephen Hauser, Dan Longo, and J. Larry Jameson. Harrison’s Principles of Internal Medicine. 16th ed. New York, NY: McGraw-Hill, Medical Pub. Division, 2004. ISBN: 9780071402354 .

Discussion Papers

SES # TOPICS READINGS
15 Paper Discussion 1 Forster, R., A. Schubel, D. Breitfeld, E. Kremmer, I. Renner-Muller, E. Wolf, and M. Lipp. “CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.” Cell 99, no. 1 (October 1, 1999): 23-33.
17 Paper Discussion 2 Fisher, G. H., F. J. Rosenberg, S. E. Straus, J. K. Dale, L. A. Middleton, A. Y. Lin, W. Strober, M. J. Lenardo, and J. M. Puck. “Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome.” Cell 81, no. 6 (June 16, 1995): 935-46.
22 Paper Discussion 3 Murali-Krishna, K., L. L. Lau, S. Sambhara, F. Lemonnier, J. Altman, and R. Ahmed. “Persistence of memory CD8 T cells in MHC class I-deficient mice.” Science 286, no. 5443 (November 12, 1999): 1377-81.
28 Paper Discussion 4 Fontenot, J. D., M. A. Gavin, and A. Y. Rudensky. “Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.” Nat Immunol 4, no. 4 (April 2003): 330-6. (Epub March 3, 2003)

Optional Readings

McMichael, A. J., and S. L. Rowland-Jones. “HIV: Bad news for stop-start therapy?” Nature 420, no. 6914 (November 28, 2002): 371, and 373.

Chaudhuri, J., M. Tian, C. Khuong, K. Chua, E. Pinaud, F. W. Alt. “Transcription-targeted DNA deamination by the AID antibody diversification enzyme.” Nature 422, no. 6933 (April 17, 2003): 726-30. (Epub April 9, 2003)

Rosen, F. S., M. D. Cooper, and R. J. Wedgwood. “The primary immunodeficiencies.” N Engl J Med 333, no. 7 (August 17, 1995): 431-40.

Course Info

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Fall 2005
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