Course Meeting Times
Lectures: 2 sessions / week, 1.5 hours / session
- Response of cells and tissues to exogenous mechanical loading.
- Endogenous mechanical forces generated by cells (viz., contractile forces generated by connective tissue cells).
- Molecular structure-mechanical properties relationships for selected connective tissues.
- Chemical composition of the extracellular matrix of tissues.
- Structure of tissues (viz., connective tissues) at the nanometer, micrometer, and millimeter length scales (including the hierarchical structure of tissues).
- Load-deformation behavior of tissues at the micrometer and millimeter scales.
- Interrelationships among the above.
Unique Aspects of the Subject
- Assessment of the response of cells and tissues to mechanical forces; discussion of mechano-transduction mechanisms.
- Discussion of contraction of connective tissue cells.
Yannas, I. V. Tissue and Organ Regeneration in Adults. New York, NY: Springer, 2001. ISBN: 9780387952147.
This book is supplemented by papers, presentations and readings.
The course grade is based entirely on the three quizzes.