This class provides an introduction to the interactions between cells and the surfaces of biomaterials. The course covers: surface chemistry and physics of selected metals, polymers, and ceramics; surface characterization methodology; modification of biomaterials surfaces; quantitative assays of cell behavior in culture; biosensors and microarrays; bulk properties of implants; and acute and chronic response to implanted biomaterials. General topics include biosensors, drug delivery, and tissue engineering.