% ipython
Python 3.8.8 (default, Apr 13 2021, 12:59:45) 
Type 'copyright', 'credits' or 'license' for more information
IPython 7.22.0 -- An enhanced Interactive Python. Type '?' for help.

Then paste
import matplotlib
matplotlib.use('macosx')
import matplotlib.pyplot as plt
plt.plot([0,1, 2, 3], [0, 4, 6, 8],'o-')
plt.show()

# To exit 
quit()