Readings

WEEK # TOPICS READINGS
1

Introduction and Overview

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No readings
2

Wine and Beer: Ethanol

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Nissen, T. L., M. C. Kielland-Brandt, et al. “Optimization of Ethanol Production in Saccharomyces cerevisiae by Metabolic Engineering of The Ammonium Assimilation.” Metab Eng. 2, no. 1 (2000): 69–77.

Ehsani, M., M. R. Fernández, et al. “Engineering of 2,3-Butanediol Dehydrogenase To Reduce Acetoin Formation by Glycerol-Overproducing, Low-Alcohol.” Applied Environmental Microbiology 75, no. 10 (2009): 3196–205.

3

Food Additives

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Yao, W., C. Chu, et al. “Display of α-amylase on The Surface of Corynebacterium glutamicum cells by Using NCgl1221 as the Anchoring Protein, and Production of Glutamate from Starch.” Arch Microbiol 191, no. 10 (2009): 751–9.

Schultz, C., A. Niebisch, et al. “Glutamate Production by Corynebacterium glutamicum: Dependence on the Oxoglutarate Dehydrogenase Inhibitor Protein OdhI and Protein Kinase PknG.” Applied Microbiology and Biotechnology 76, no. 3 (2007): 691–700.

4

Amino Acids

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Ikeda, M., J. Ohnishi, et al. “A Genome-based Approach to Create a Minimally Mutated Corynebacterium Glutamicum Strain for Efficient L-lysine Production.” Journal of Industrial Microbiology and Biotechnology 33, no. 7 (2006): 610–5.

Becker, J., O. Zelder, et al. “From Zero to Hero—Design-based Systems Metabolic Engineering of Corynebacterium Glutamicum for L-lysine Production.” Metabolic Engineering 13, no. 2 (2011): 159–68.

5

Enzymes

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Ahmad, S., M. Z. Kamal, et al. “Thermostable Bacillus Subtilis Lipases: In Vitro Evolution and Structural Insight.” Journal of Molecular Biology 381, no. 2 (2008): 324–40.

Pushpam, P. L., R. Thangamani, et al. “Identification and Characterization of Alkaline Serine Protease from Goat Skin Surface Metagenome.” AMB Express 1, no. 1 (2011): 3.

6

Specialty Chemicals

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Okino, S., R. Noburyu, et al. “An Efficient Succinic Acid Production Process in a Metabolically Engineered Corynebacterium Glutamicum Strain.” Applied Microbiology and Biotechnology 81, no. 3 (2008): 459–64.

Litsanov, B., A. Kabus, et al. “Efficient Aerobic Succinate Production from Glucose in Minimal Medium with Corynebacterium Glutamicum.” Microbial Biotechnology 5, no. 1 (2012): 116–28.

7

Field Trip

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No readings
8

Biofuels I

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Atsumi, S., H. Taizo, et al. “Non-fermentative Pathways for Synthesis of Branched-chain Higher Alcohols as Biofuels.” Nature 451 (2008): 86–9.

Dellomonaco, C., J. M. Clomburg, et al. “Engineered Reversal of the β-oxidation Cycle for the Synthesis of Fuels and Chemicals.” Nature 476, no. 7360 (2011): 355–9.

9

Biofuels II

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Steen, E. J., Y. Kang, et al. “Microbial Production of Fatty-acid-derived Fuels and Chemicals from Plant Biomass.” Nature 463 (2010): 559–62.

Alvarez, A. F., H. M. Alvarez, et al. “Cloning and Characterization of a Gene Involved in Triacylglycerol Biosynthesis and Identification of Additional Homologous Genes in the Oleaginous Bacterium Rhodococcus Opacus PD630.” Microbiology 154 (2008): 2327–35.

10

Biopolymers I

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Tian, J., A. J. Sinskey, et al. “Kinetic Studies of Polyhydroxybutyrate Granule Formation in Wautersia Eutropha H16 by Transmission Electron Microscopy.” Journal of Bacteriology 187, no. 11 (2005): 3814–24.

Budde, C. F., S. L. Riedel, et al. “Production of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from Plant Oil by Engineered Ralstonia Eutropha Strains.” Applied and Environmental Microbiology 77 (2011): 2847–54.

11

Biopolymers II

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Taguchi, S., M. Yamada, et al. “A Microbial Factory for Lactate-based Polyesters Using a Lactate-polymerizing Enzyme.” Proceedings of the National Academy of Sciences 105, no. 45 (2008): 17323–7.

Lin, K., Y. Elbahloul, et al. “Physiological Conditions Conducive to High Cell Density and High Cyanophycin Content in Ralstonia Eutropha Strain H16 Possessing a KDPG Aldolase Gene-dependent Addiction System.” Applied Microbiology and Biotechnology 93, no. 5 (2012): 1885–94.

12

Biopharmaceuticals and Biosensors

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Parlane, N. A., Grage K. “Vaccines Displaying Mycobacterial Proteins on Biopolyester Beads Stimulate Cellular Immunity and Induce Protection Against Tuberculosis.” Clinical and Vaccine Immunology 19, no. 1 (2012): 37–44.

Bahl, M. I., L. H. Hansen, et al. “In Vivo Detection and Quantification of Tetracycline by Use of a Whole-cell Biosensor in the Rat Intestine.” Antimicrobial Agents and Chemotherapy 48, no. 4 (2004): 1112–7.

13

Oral Presentations

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No readings