Course Requirements

  1. Attendance and participation in all classes. Each Thursday before class (by 1:00 PM) each student will submit two questions or statements (one for each paper) via e-mail to the instructors. These questions or statements can be a criticism of an experiment, a proposed follow-up experiment to the work done, or simply a question about a technique used in the paper.
  2. Based on the material covered in class, write a 2-page project proposal. This proposal will outline experiments to address a frontier problem in the field.
  3. Oral presentation. Students will present 2 page research proposals (above) to the class. Each will be a 10-15 min slideshow presentation describing background, experiments and expected results.

Guidelines for Presentations (PDF)

  • ~8 Slides Total
  • 10 minutes Total (+ 5 mins of Questions at the End)
  • Title Slide
  • Introduction / Background (1-2 Slides)
    • What is the relevant information we need to know to understand why you are proposing this research?
    • What’s your motivation?
    • What is the gap in understanding you aim to fill?
    • Example: For this week’s papers, you would describe how
      • RAR fusion proteins result in leukemias that respond differently to treatment, or
      • MLL fusion proteins can cause leukemias, but the mechanism is unknown.
    • Use figures.
  • Question You wish to Answer / Hypothesis to Test (1 Slide)
    • State this clearly and succinctly.
    • What precisely do you hope to accomplish with your proposed research?
    • Similar to your specific aims in your written proposals.
  • Experimental Approach / System (1-2 Slides)
    • Describe the system you will use and the experiments you will conduct to address your question of interest.
    • Use figures.
  • Expected Results (2-3 Slides)
    • What type of data will you get?
    • How will you draw conclusions from the data?
    • What are the possible / expected results you might obtain, and how do these fit into possible models?
    • You can use mock figures to clarify possible outcomes.
  • Conclusions / What You Expect to Learn / Follow-up (1 Slide)
    • If your research is successful, what do you hope to learn from it?
    • How will this change our understanding of this problem, and how might one follow up on these results?
Course Info
As Taught In
Fall 2006
Learning Resource Types
assignment Presentation Assignments