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Choose one of the possible choices for each question:
- Benzodiazepines are
- GABA non competitive antagonists
- GABA non competitive agonists
- GABA competitive antagonists
- The Topic Anesthetic Lidocaine
- blocks the Na+ channels
- blocks the Cl- channels
- blocks the Na+/K+ pump
- The Drug NBQX is
- a NMDA receptors antagonist
- a AMPA receptors antagonist
- a GABA receptors agonist
- The “Potency of a Drug” is
- the affinity of the drug for its receptor
- the biological effects exerted by the drug on its target
- the measure of the turn over of a drug
- The Receptors for Dopamine or Norepinephrine are
- all metabotropic
- all ionotropic
- both
- Atropin is
- a muscarinic receptor antagonist
- a pupillary dilatator
- both
- In Parkinson Disease the Control of Movements is Modulated by Drugs that Affect
- cholinergic and dopaminergic transmission
- gabaergic and cholinergic transmission
- noradrenergic and serotoninergic transmission
- Botulinum Toxins
- act in the synapses between two neurons
- block acetylcholine release
- induce a massive release of acetylcholine
- Reserpine acts
- on the noradrenergic system
- on the serotoninergic system
- on both noradrenergic and serotoninergic systems
- The Noradrenaline Producing Neurons are Mainly Localized
- in the locus coeruleous
- in the substantia nigra
- in the hippocampus
- Which of the Following Drugs Affects Specifically the Serotoninergic System?
- Reserpine
- Fluoxatine
- Barbiturates
- Which of the Following Drugs Induce Dependance
- Valium
- Prozac
- Lidocaine
- Which of the Following Drugs is NOT used to Treat Anxiety Disorders?
- barbiturates
- benzodiazepines
- Vesamicol
- Which Kind of Diet would Increase Serotonin Production?
- carbohydrates-rich diet
- protein-rich diet
- lipid-rich diet
- What are the Possible Side-effects of CNS Depressants?
- sedation
- respiratory depression
- both
- What is the Starting Reagent for the Synthesis of Serotonin?
- tyrosine
- choline
- tryptophan
- Toxin in the Venom of the Black Widow Spider Induces
- a massive release of acetylcholine
- blockade of GABAergic transmission
- reduction of acetylcholine transmission
- Which of the Following Drugs is an Inhibitor of Acetylcholinesterase?
- Neostygmine
- Nicotine
- Atropine
- Firing of the Neurons in the Locus Coeruleus (LC) is Activated by
- corticotrophin releasing factor
- GABA
- serotonin
- Possible Antidepressants are
- Monoamineoxidase’s inhibitors
- Cortisol
- Domoic Acid
LEC # | TOPICS |
---|---|
1 | Basics of neuroscience (PDF - 2.5 MB) |
2 | The neurotransmitter systems (PDF - 1.7 MB) |
3 | Neuropsychiatric disorders: anxiety, mood disorders (PDF) |
4 | Neuropsychiatric disorders: schizophrenia, final exam (PDF) |
Course Meeting Times
Lectures: 1 session / week, 1 hour / session
Course Description
The neuropharmacology course will discuss the drug-induced changes in functioning of the nervous system. The specific focus of this course will be to provide a description of the cellular and molecular actions of drugs on synaptic transmission. This course will also refer to specific diseases of the nervous system and their treatment in addition to giving an overview of the techniques used for the study of neuropharmacology.
Lecture Schedule
Four 1 hour lectures in January.
Course Prerequisites and Requirements
This course is open to both graduate and undergraduate students with a basic knowledge of neuroscience principles.
Course Requirements
Outline
The key topics covered in this course are listed below:
- Introduction to neuropharmacology
- Principles of neurobiology
- Neurotransmitter systems:
- Glutamate and GABA
- Catecholamines
- Acetylcholine and serotonin
- Disorders of the nervous systems and their treatment
- Techniques in neuropharmacology
Recommended Texts
The following texts are recommended for this course:
Meyer, Jerrold S., and Linda F. Quenzer. Psychopharmacology: Drugs, the Brain and Behavior. 1st ed. Sunderland, MA: Sinauer Associates, 2004. ISBN: 9780878935345.
Nestler, Eric, Steven Hyman, and Robert Malenka. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience. 2nd ed. New York, NY: McGraw-Hill Professional, 2008. ISBN: 9780071481274.
Cooper, Jack R., Floyd E. Bloom, and Robert H. Roth. The Biochemical Basis of Neuropharmacology. 8th ed. Oxford, USA: Oxford University Press, 2002. ISBN: 9780195140088.
Grading
There will be a final exam for this course. The exam will be a pass/fail multiple choice exam.
Calendar
LEC # | TOPICS |
---|---|
1 | Basics of neuroscience |
2 | The neurotransmitter systems |
3 | Neuropsychiatric disorders: anxiety, mood disorders |
4 | Neuropsychiatric disorders: schizophrenia, final exam |