Foundations of Computational and Systems Biology
Lecture 1: Introduction to Computational and Systems Biology
Lecture 2: Local Alignment (BLAST) and Statistics
Lecture 3: Global Alignment of Protein Sequences (NW, SW, PAM, BLOSUM)
Lecture 4: Comparative Genomic Analysis of Gene Regulation
Lecture 5: Library Complexity and Short Read Alignment (Mapping)
Lecture 6: Genome Assembly
Leture 7: ChIP-seq Analysis; DNA-protein Interactions
Lecture 8: RNA-sequence Analysis: Expression, Isoforms
Lecture 9: Modeling and Discovery of Sequence Motifs
Lecture 10: Markov and Hidden Markov Models of Genomic and Protein Features
Lecture 11: RNA Secondary Structure – Biological Functions and Prediction
Leture 12: Introduction to Protein Structure; Structure Comparison and Classification
Lecture 13: Predicting Protein Structure
Lecture 14: Predicting Protein Interactions
Lecture 15: Gene Regulatory Networks
Lecture 16: Protein Interaction Networks
Lecture 17: Logic Modeling of Cell Signaling Networks
Lecture 18: Analysis of Chromatin Structure
Lecture 19: Discovering Quantitative Trait Loci (QTLs)
Lecture 20: Human Genetics, SNPs, and Genome Wide Associate Studies
Lecture 21: Synthetic Biology: From Parts to Modules to Therapeutic Systems
Lecture 22: Causality, Natural Computing, and Engineering Genomes
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