Session 3: Enzymes and Catalysis

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Lecture Topics

  • Definition of a Catalyst
  • Conceptualization of Catalysis using Transition State Theory
  • How has Nature Evolved Enzymes to Lower the Activation Barrier?
  • The Second Important Property of Enzymes is their Specificity


  • Chapter 11: Enzymatic Catalysis
    • General Properties of Enzyme
    • Activation Energy and the Reaction Coordinate
    • Catalytic Mechanisms
    • Serine Proteases

Lecture Video: Enzymes and Catalysis

In this classroom lecture, Professor Stubbe focuses on enzymes as catalysts. She describes the theory and mechanics of catalysis and explains why enzymes are so important.

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Lecture Notes

Problem Set & Solutions

Problem Solving Video: Problem Set 2, Problem 1: Primary Structure

This problem is about elucidating the primary structure of a protein. Dr. Fedeles uses traditional chemical methods to analyze the data and produce a big picture result. This is the very same process by which discoveries are made.

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