20.320 | Fall 2012 | Undergraduate

Analysis of Biomolecular and Cellular Systems

Modeling of Cellular Systems

Protein Networks Project

This design project accompanies the Modeling of Cellular Systems section.

Bioreactors are steady-state mixed tanks that keep bacteria in permanent exponential growth while continuously diluting with nutrient-rich broth and removing both cells and reaction products. They are great tools for the biochemical engineering industry, but monitoring them is not trivial. There are many factors that can affect the health of the system’s bacteria, and only some of them (temperature, pressure) can be measured physically. Things like nutrient levels and the presence of contaminants must be measured through sampling, and this is the process that you’ll try to simplify in this project.

Protein Networks Project Guidelines and Directions (PDF)

run_sensorODE.m (M)

sensorODE.m (M)

sensorODE_solver.m (M)

Tutorial: Generating fluorescence vs. concentration plots (PDF)    
Design Project – Part A (PDF)

Data for Design Project – Part A (CSV)


Solutions to Design Project – Part A (PDF)

Course Info

As Taught In
Fall 2012
Learning Resource Types
Problem Sets with Solutions
Exams with Solutions
Lecture Notes
Instructor Insights