20.450 | Spring 2005 | Graduate

Molecular and Cellular Pathophysiology (BE.450)


Students are required to make an in-class presentation reviewing one or two of the assigned papers. The following table gives the assigned papers and an example of the student presentation.

4-5 Inflammation  

Muller, A., et al. “Involvement of chemokine receptors in breast cancer metastasis.” Nature 410, no. 6824 (March 1, 2001): 50-6.

Liotta, L. A. “An attractive force in metastasis.” Nature 410, no. 6824 (March 1, 2001): 24-5.

7-9 Immunity   Prasad, S. J., et al. “Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells.” Journal of Immunology 174, no. 1 (January 1, 2005): 90-8.
10 Neoplasia  

Li, et al. “Accurate qualitative and quantitative proteomic analysis of clinical hepatocellular carcinoma using laser capture microdissection coupled with isotope-coded affinity tag and two-dimensional liquid chromatography mass spectrometry.” Molecular and Cellular Proteomics 3, no. 4 (April 2004): 399-409.

Ding, S. J., et al. “From proteomic analysis to clinical significance: overexpression of cytokeratin 19 correlates with hepatocellular carcinoma metastasis.” Molecular and Cellular Proteomics 3, no. 1 (January 2004): 73-81.

15-16 Hepatocarcinogenesis (PDF) (Courtesy of Erin Bridgeford and Nancy Guillén. Used with permission.) Iizuka, N., et al. “Self-organizing-map-based molecular signature representing the development of hepatocellular carcinoma.” FEBS Letters 579, no. 5 (February 14, 2005): 1089-100.
19-22 Special Topic    

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As Taught In
Spring 2005
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