7.27 | Spring 2006 | Undergraduate

Principles of Human Disease


The following reading selections are from:

Janeway, Charles A., Jr., Paul Travers, Mark Walport, and Mark J. Shlomchik. Immunobiology. 5th ed. New York, NY: Garland Publishing, 2001. ISBN: 9780815336426. (Courtesy of the National Center for Biotechnology Information’s Web site).

Basic Concepts in Immunology

The Components of the Immune System

Principles of Innate and Adaptive Immunity

The Recognition and Effector Mechanisms of Adaptive Immunity

Innate Immunity

The Front Line of Host Defense

The Complement System and Innate Immunity

Receptors of the Innate Immune System

Induced Innate Responses to Infection

Antigen Recognition by B-cell and T-cell Receptors

The Structure of a Typical Antibody Molecule

The Interaction of the Antibody Molecule with Specific Antigen

Antigen Recognition by T-cells

Rabbit Virulence:

Saint, K. M., N. French, and P. Kerr. “Genetic variation in Australian isolates of myxoma virus: an evolutionary and epidemiological study.” Arch Virol 146, no. 6 (2001): 1105-23.

The following reading selections are from:

Strachan, Tom, and Andrew P. Read. Human Molecular Genetics. 2nd ed. New York, NY: John Wiley & Sons Inc., 1999. ISBN: 9780471330615. (Courtesy of the National Center for Biotechnology Information’s Web site).

Molecular Pathology

Genetic Testing

PCR and Sequencing as Used in Human Genetics

Nucleic Acid Hybridization Assays Used in Human Genetics

Genes in Pedigrees

Glucose-6-Phosphate Deficiency


Course Info

As Taught In
Spring 2006
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Problem Sets
Written Assignments