Neuropharmacology

Exams

Choose one of the possible choices for each question:

1. Benzodiazepines are

---

1. GABA non competitive antagonists
2. GABA non competitive agonists
3. GABA competitive antagonists

2. The Topic Anesthetic Lidocaine

---

1. blocks the Na+ channels
2. blocks the Cl- channels
3. blocks the Na+/K+ pump

3. The Drug NBQX is

---

1. a NMDA receptors antagonist
2. a AMPA receptors antagonist
3. a GABA receptors agonist

4. The “Potency of a Drug” is

---

1. the affinity of the drug for its receptor
2. the biological effects exerted by the drug on its target
3. the measure of the turn over of a drug

5. The Receptors for Dopamine or Norepinephrine are

---

1. all metabotropic
2. all ionotropic
3. both

6. Atropin is

---

1. a muscarinic receptor antagonist
2. a pupillary dilatator
3. both

7. In Parkinson Disease the Control of Movements is Modulated by Drugs that Affect

---

1. cholinergic and dopaminergic transmission
2. gabaergic and cholinergic transmission
3. noradrenergic and serotoninergic transmission

8. Botulinum Toxins

---

1. act in the synapses between two neurons
2. block acetylcholine release
3. induce a massive release of acetylcholine

9. Reserpine acts

---

1. on the noradrenergic system
2. on the serotoninergic system
3. on both noradrenergic and serotoninergic systems

10. The Noradrenaline Producing Neurons are Mainly Localized

---

1. in the locus coeruleous
2. in the substantia nigra
3. in the hippocampus

11. Which of the Following Drugs Affects Specifically the Serotoninergic System?

---

1. Reserpine
2. Fluoxatine
3. Barbiturates

12. Which of the Following Drugs Induce Dependance

---

1. Valium
2. Prozac
3. Lidocaine

13. Which of the Following Drugs is NOT used to Treat Anxiety Disorders?

---

1. barbiturates
2. benzodiazepines
3. Vesamicol

14. Which Kind of Diet would Increase Serotonin Production?

---

1. carbohydrates-rich diet
2. protein-rich diet
3. lipid-rich diet

15. What are the Possible Side-effects of CNS Depressants?

---

1. sedation
2. respiratory depression
3. both

16. What is the Starting Reagent for the Synthesis of Serotonin?

---

1. tyrosine
2. choline
3. tryptophan

17. Toxin in the Venom of the Black Widow Spider Induces

---

1. a massive release of acetylcholine
2. blockade of GABAergic transmission
3. reduction of acetylcholine transmission

18. Which of the Following Drugs is an Inhibitor of Acetylcholinesterase?

---

1. Neostygmine
2. Nicotine
3. Atropine

19. Firing of the Neurons in the Locus Coeruleus (LC) is Activated by

---

1. corticotrophin releasing factor
2. GABA
3. serotonin

20. Possible Antidepressants are

---

1. Monoamineoxidase’s inhibitors
2. Cortisol
3. Domoic Acid