Course Meeting Times
Lectures: 2 sessions / week, 1.5 hours / session
20.106J/1.084J: Systems Microbiology
Microbiology from a systems perspective.
Prerequisites
5.111, 5.112 or 3.091; 7.012, 7.013, or 7.014
Course Textbook
Madigan, Michael, and John Martinko. Brock Biology of Microorganisms. 11th ed. Upper Saddle River, NJ: Pearson Prentice Hall, 2005. ISBN: 9780131443297.
Grading
| ACTIVITIES | PERCENTAGE |
|---|---|
| Problem Sets (~1 every 2 weeks) | 25% |
| Midterm I | 20% |
| Midterm II | 20% |
| Final Exam | 35% |
Calendar
| Lec # | TOPICS | LECTURERS | KEY DATES |
|---|---|---|---|
| 1 | Early Earth/Microbial Evolution | Prof. Ed DeLong | |
| 2 | Cell Structure/Function | Prof. Ed DeLong | Problem set 1 out |
| 3 | Biological Energy Conservation | Prof. Ed DeLong | |
| 4 | Microbial Growth | Prof. David Schauer | Problem set 1 due |
| 5 | Metabolic Regulation | Prof. Ed DeLong | Problem set 2 out |
| 6 | Virology | Prof. David Schauer | |
| 7 | Information Flow in Biological Systems | Prof. Ed DeLong | Problem set 2 due |
| Midterm I | |||
| 8 | Regulation of Cell Activity | Prof. Ed DeLong | Problem set 3 out |
| 9 | Genetic Exchange in Bacteria | Prof. Ed DeLong | |
| 10 | Experimental Evolution: Optimization of Metabolic Systems | Guest Lecturer, Prof. Christopher Marx from Harvard | Problem set 3 due |
| 11 | Genomics I | Prof. Ed DeLong | |
| 12 | Genomics II | Prof. Ed DeLong | Problem set 4 out |
| 13 | Metabolic Diversity I | Prof. Ed DeLong | |
| 14 | Metabolic Diversity II | Prof. Ed DeLong | |
| 15 | Microbial Ecology | Prof. Ed DeLong | Problem set 4 due |
| Midterm II | |||
| 16 | Microbial Growth Control | Prof. David Schauer | Problem set 5 out |
| 17 | Microbe-host Interactions | Prof. David Schauer | |
| 18 | Immunology I | Megan McBee | |
| 19 | Immunology II | Megan McBee | Problem set 5 due |
| 20 | Diagnostic Microbiology | Prof. David Schauer | Problem set 6 out |
| 21 | Person-to-person Transmission | Prof. David Schauer | |
| 22 | Epidemiology | Megan McBee | Problem set 6 due |
| 23 | Animal- and Arthropod-transmitted Diseases | Prof. David Schauer | |
| 24 | Review | Prof. David Schauer | |
| Final Exam |
