Parkinson's Disease Workshop

Readings

The following readings are cited in the lecture notes, or are otherwise associated with a given topic.

SES #	Topics	READINGS
1	Cognition in Parkinson’s Disease	Ashby, Noble, Filoteo, Waldron, and Ell. “Category Learning Deficits in Parkinson’s Disease.” Neuropsychology 17, no. 1 (2003): 115-124. Brown, Marsden, Quinn, and Wyke. “Alterations in Cognitive Performance and Affect-Arousal State During Fluctuations in Motor Function in Parkinson’s Disease.” Journal of Neurology, Neurosurgery & Psychiatry 47, no. 5 (1984): 454-65. Cools, Barker, Sahakian, and Robbins. “Enhanced or Impaired Cognitive Function in Parkinson’s Disease as a Function of Dopaminergic Medication and Task Demands.” Cerebral Cortex 11 (2001): 1136-1143. Cools. “Dopaminergic Modulation of Cognitive Function: Implications for L-DOPA Treatment in Parkinson’s Disease.” Neuroscience and Biobehavioral Reviews 30 (2006): 1-23. Cronin-Golomb, Corkin, and Growdon. “Impaired Problem Solving in Parkinson’s Disease: Impact of a Set-Shifting Deficit.” Neuropsychologia 32 (1994): 579-593. Gabrieli, Singh, Stebbins, and Goetz. “Reduced Working Memory Span in Parkinson’s Disease: Evidence for the Role of a Frontostriatal System in Working and Strategic Memory.” Neuropsychology 10 (1996): 322-332. Growdon, Corkin, and Rosen. “Distinctive Aspects of Cognitive Dysfunction in Parkinson’s Disease.” Advances in Neurology 53 (1990): 365-376. Hodgson, Tiesman, Owen, and Kennard. “Abnormal Gaze Strategies During Problem Solving in Parkinson’s Disease.” Neuropsychologia 40 (2002): 411-422. Katzen, Levin, and Llabre. “Age of Disease Onset Influences Cognition in Parkinson’s Disease.” Journal of the International Neuropsychological 4, no. 3 (1998): 285-290. Locascio, Corkin, and Growdon. “Relation Between Clinical Characteristics of Parkinson’s Disease and Cognitive Decline.” Journal of Clinical and Experimental Neuropsychology 25, no. 1 (2003): 94-109. Mayeuz, Stern, Rosenstein, Marder, Hauser, Cote, and Fahn. “An Estimate of the Prevalence of Dementia in Idiopathic Parkinson’s Disease.” Archives of Neurology 45 (1988): 260-262. Ogden, Growdon, and Corkin. “Deficits on Visuospatial Tests Involving Forward Planning in High-functioning Parkinsonians.” Neuropsychiatry, Neuropsychology, and Behavioral Neuroscience 105 (1990): 326-342. Parkinson. An Essay on the Shaking Palsy. London, UK: Sherwood, Neely and Jones, 1817. Postle, Jonides, Smith, Corkin, and Growdon. “Spatial, But Not Object, Delayed Response is Impaired in Early Parkinson’s Disease.” Neuropsychology 11, no. 2 (1997): 171-179. Sharpe. “Is There A Divided Attention Deficit in Patients with Early Parkinson’s Disease?” Cortex 32 (1996): 747-753. Woodward, Bub, and Hunter. “Task Switching Deficits Associated with Parkinson’s Disease Reflect Depleted Attentional Resources.” Neuropsychologia 40 (2002): 1948-1955.
2	Neuropathology and Structural Neuroimaging in Parkinson’s Disease	Damier, Hirsch, Agid, and Graybiel. “The Substantia Nigra of the Human Brain II. Patterns of Loss of Dopamine-containing Neurons in Parkinson’s Disease.” Brain 122 (1999): 1437-1448. Whone, Moore, Piccini, and Brooks. “Plasticity of the Nigropallidal Pathway in Parkinson’s Disease.” Annals of Neurology 53 (2003): 206-213. Camicioli, Moore, Kinney, Corbridge, Glassberg, and Kaye. “Parkinson’s Disease is Associated with Hippocampal Atrophy.” Movement Disorders 18, no. 7 (2003): 784-790. Junque, Ramirez-Ruiz, Tolosa, Summerfield, Marti, Pastor, Gomez-Anson, and Mercader. “Amygdalar and Hippocampal MRI Volumetric Reductions.” Parkinson’s Disease with Dementia 20, no. 5 (2005): 540-544. Harding, Stimson, Henderson, and Halliday. “Clinical Correlates of Selective Pathology in the Amygdala of Patients with Parkinson’s Disease.” Brain 125 (2002): 2431-2445. Zarow, Lyness, Mortimer, and Chui. “Neuronal Loss is Greater in the Locus Coeruleus than Nucleus Basalis and Substantia Nigra in Alzheimer and Parkinson Diseases.” Archives of Neurology 60 (2003): 337-341. Rye, and DeLong. “Time to Focus on the Locus.” Archives of Neurology 60, no. 320 (2003). Pedersen, Marner, Pakkenberg, and Pakkenberg. “No Global Loss of Neocortical Neurons in Parkinson’s Disease: A Quantitative Stereological Study.” Movement Disorders 20, no. 2 (2004): 164-171. Yoshikawa, Nakata, Yamada, and Nakagawa. “Early Pathological Changes in the Parkinsonian Brain Demonstrated by Diffusion Tensor MRI.” Journal of Neurological Neurosurgery and Psychiatry 75 (2004): 481-484.
3	Genetics of Parkinson’s Disease	Khan, Jain, Lynch, Pavese, et al. “Mutations in the Gene LRRK2 Encoding Dardarin (PARK8) Cause Familial Parkinson’s Disease: Clinical, Pathological, Olfactory and Functional Imaging and Genetic Data.” Brain 128 (2005): 2786-2796. Sun, Latourelle, Wooten, Lew, et al. “Heterozygosity for Parkin Mutation Influences Onset Age in Familial Parkinson’s Disease.” Archives of Neurology 63 (2006): 826-832. Sinha, Racette, Perlmutter, and Parsian. “Prevalence of Parkin Gene Mutations and Variations in Idiopathic Parkinson’s Disease.” Parkinsonism and Related Disorders 11 (2005): 341-347. Hu, Scherfler, Khan, Hajinal, Lees, Quinn, Wood, and Brooks. “Nigral Degeneration and Striatal Dopaminergic Dysfunction in Idiopathic and Parkin-linked Parkinson’s Disease.” Movement Disorders 21, no. 3 (2006): 290-305. Foltynie, Goldberg, Lewis, Blackwell, Kolachana, Weinberger, Robbins, and Barker. “Planning Ability in Parkinson’s Disease is Influenced by the COMT Val 158 met Polymorphism.” Movement Disorders 19, no. 8 (2004): 885-891. Cools, Barker, Sahakian, and Robbins. “Enhanced or Impaired Cognitive Function in Parkinson’s Disease as a Function of Dopaminergic Medication and Task Demands.” Cerebral Cortex 11 (2001): 1136-1143. DiMonte, Lavasani, and Manning-Bog. “Environmental Factors in Parkinson’s Disease.” Neurotoxicology 23 (2002): 487-502. Betarbet, Sherer, MacKenzie, and Garcia-Osuna. “Chronic Systemic Pesticide Exposure Reproduces Features of Parkinson’s Disease.” Nature Neuroscience 3 (2000): 1301-1306. Yesavage. “Spatial Test for Agricultural Pesticide ‘Blow-in’ Effect on Prevalence of Parkinson’s Disease.” Journal of Geriatric Psychiatry and Neurology 19, no. 1 (2006): 32-35. Benbunan, Korczyn, and Giladi. “Parkin Mutation Associated Parkinsonism and Cognitve Decline, Comparison to Early Onset Parkinson’s Disease.” Journal of Neural Transmission 111, no. 1 (2004): 47-57. Gilks, Abou-Sleiman, Gandhi, Jain, and Singleton. “A Common LRRK2 Mutation in Idiopathic Parkinson’s Disease.” Lancet 365 (2005): 415-416. Hedrich, Marder, Harris, Kann, Lynch, et al. “Evaluation of 50 Probands with Early-onset Parkinson’s Disease for Parkin Mutations.” Neurology 58, no. 8 (2002): 1239-1246. Jankovic. “Searching for a Relationship between Manganese and Welding and Parkinson’s Disease.” Neurology 64, no. 12 (2005): 2021-2028. Khan, Graham, Critchley, Schrag, Wood, et al. “Parkin Disease: A Phenotypic Study of a Large Case Series.” Brain 126, no. 6 (2003): 1279-1292. Klein, Hedrich, Wellenbrook, Kann, Harris, et al. “Frequency of Parkin Mutations in Late-onset Parkinson’s Disease.” Annals of Neurology 54, no. 3 (2003): 415-416. Lesge, Ibanez, Lohmann, Pollak, Tison, et al. “G2019S LRRK2 Mutation in French and North African Families with Parkinson’s Disease.” Annals of Neurology 58, no. 5 (2005): 784-787. Lohmann, Periquet, Bonifati, Wood, De Michele, et al. “How Much Phenotypic Variation Can Be Attributed to Parkin Genotype?” Annals of Neurology 54, no. 2 (2003): 176-185. Piccini, Burn, Ceravolo, Maraganore, and Brooks. “The Role of Inheritance in Sporadic Parkinson’s Disease: Evidence from a Longitudinal Study of Dogaminergic Function in Twins.” Annals of Neurology 45, no. 5 (1999): 577-582. Tanner, Ottman, Goldman, Ellenberg, Chan, et al. “Parkinson’s Disease in Twins: An Etiologic Study.” Journal of the American Medical Association 281, no. 4 (1999): 341-346. Wirdefeldt, Gatz, Schalling, and Pederson. “No Evidence for Heritability of Parkinson’s Disease in Swedish Twins.” Neurology 63, no. 2 (2004): 305-311. Pankratz, Nichols, Uniacke, Halter, Murrell, et al. “Genome-wide Linkage Analysis and Evidence of Gene-by-gene Interactions in a Sample of 362 Multiplex Parkinson Disease Families.” Human Molecular Genetics 12, no. 20 (2003): 2599-2608.
4	Cognitive Control Processes and Working Memory in Parkinson’s Disease	Cools, Barker, Sahakian, and Robbins. “Enhanced or Impaired Cognitive Function in Parkinson’s Disease as a Function of Dopaminergic Medication and Task Demands.” Cerebral Cortex 11 (2001): 1136-1143. Cools, Altamirano, and D’Esposito. “Reversal Learning in Parkinson’s Disease Depends on Medication Status and Outcome Valence.” Neuropsychologia 44 (2006): 1663-1673. Cronin-Golomb, Corkin, and Growdon. “Impaired Problem Solving in Parkinson’s Disease: Impact of a Set-shifting Deficit.” Neuropsychologia 32 (1994): 579-593. Lewis, Foltynie, Blackwell, Robbins, Owen, and Barker. “Heterogeneity of Parkinson’s Disease in the Early Clinical Stages Using a Data Driven Approach.” Journal of Neurological Neurosurgery Psychiatry 76 (2005): 343-348. Lewis, Cools, Robbins, Dove, Barker, and Owen. “Using Executive Heterogeneity to Explore the Nature of Working Memory Deficits in Parkinson’s Disease.” Neuropsychologia 41 (2003): 645-654. Owen, James, Leigh, Summers, Marsden, Quinn, Lange, and Robbins. “Fronto-striatal Cognitive Deficits at Different Stages of Parkinson’s Disease.” Brain 115 (1992): 1727-1751. Owen, Iddon, Hodges, Summers, and Robbins. “Spatial and Non-spatial Working Memory at Different Stages of Parkinson’s Disease.” Neuropsychologia 35, no. 4 (1997): 519-532. Lewis, Dove, Robbins, Barker, and Owen. “Cognitive Impairments in Early Parkinson’s Disease Are Accompanied by Reductions in Activity in Frontostriatal Neural Circuitry.” The Journal of Neuroscience 23, no. 15 (1997): 6351-6356. Lewis, Slabosz, Robbins, Barker, and Owen. “Dopaminergic Basis for Deficits in Working Memory But Not Attentional Set-shifting in Parkinson’s Disease.” Neuropsychologia 43 (2005): 823-832. Fearnley, and Lees. “Ageing and Parkinson’s Disease: Substantia Nigra Regional Selectivity.” Brain; A Journal of Neurology 114, no. 5 (1991): 2283-2301. Kish, Shannak, and Hornykiewicz. “Uneven Pattern of Dopamine Loss in the Striatum of Patients with Idiopathic Parkinson’s Disease, Pathophysiologic and Clinical Implications.” The New England Journal of Medicine 318, no. 14 (1988): 876-880. Middleton, and Strick. “Basal Ganglia and Cerebellar Loops: Motor and Cognitive Circuits.” Brain Research 31, nos. 2-3 (2000): 236-250. ———. “Basal Ganglia Output and Cognition: Evidence from Anatomical, Behavioral, and Clinical Studies.” Brain and Cognition 42, no. 2 (2000): 183-200. Postle, Locascio, Corkin, and Growdon. “The Time Course of Spatial and Object Learning in Parkinson’s Disease.” Neuropsychologia 35 (1997): 1413-1422. Uhl, Hedreen, and Prince. “Parkinson’s Disease: Loss of Neurons from the Ventral Tegmental Area Contralateral to Therapeutic Surgical Lesions.” Neurology 35, no. 8 (1985): 1215-1218.
5	A Systems Neuroscience Approach to Memory	Aggleton, Vann, Denby, Dix, Mayes, Roberts, and Yonelinas. “Sparing of the Familiarity Component of Recognition Memory in a Patient with Hippocampal Pathology.” Neuropsychologia 43 (2005): 1810-1823. Hockley, and Consoli. “Familiarity and Recollection in Item and Associative Recognition.” Memory and Cognition 27, no. 4 (1999): 657-664. Mayes, Holdstock, Isaac, et al. “Associative Recognition in a Patient with Selective Hippocampal Lesions and Relatively Normal Item Recognition.” Hippocampus 14 (2004): 763-784. Vargha-Khadem, Gadian, Watkins, Connelly, Van Paesschen, and Mishkin. “Differential Effects of Early Hippocampal Pathology on Episodic and Semantic Memory.” Science 277 (1997): 376-380. Davachi, and Wagner. “Hippocampal Contributions to Episodic Encoding: Insights from Relational and Item-based Learning.” Journal of Neurophysiology 88 (2002): 982-990. Ranganath, Yonelinas, Cohen, Dy, Tom, and D’Esposito. “Dissociable Correlates of Recollection and Familiarity Within the Medial Temporal Lobes.” Neuropsychologia 42 (2003): 2-13. Giovnello, Verfaellie, and Keane. “Disproportionate Deficit in Associative Recognition Relative to Item Recognition in Global Amnesia.” Cognitive, Affective, and Behavioral Neuroscience 3, no. 3 (2003): 186-184.
6	Long-term Declarative Memory in Parkinson Disease	Ivory, Knight, Longmore, and Davies. “Verbal Memory in Non-demented Patients with Idiopathic Parkinson’s Disease.” Neuropsychologia 37 (1999): 817-828. Higginson, Wheelock, Carroll, and Sigvardt. “Recognition Memory in Parkinson’s Disease With and Without Dementia: Evidence Inconsistent with the Retrieval Deficit Hypothesis.” Journal of Clinical and Experimental Neuropsychology 27 (2005): 516-528. Minamoto, Tachibana, Sugita, and Okita. “Recognition Memory in Normal Aging and Parkinson’s Disease: Behavioral an Electrophysiologic Measures.” Cognitive Brain Research 11 (2001): 23-32. Davidson, Anaki, Saint-Cyr, Chow, and Moscovitch. “Exploring the Recognition Memory Deficit in Parkinson’s Disease: Estimates of Recollection versus Familiarity.” Brain 129 (2006): 1768-1779. Souchay, Isingrini, and Gil. “Metamemory Monitoring and Parkinson’s Disease.” Journal of Clinical and Experimental Neuropsychology 28 (2006): 618-630. Glozman, Levin, and Lycheva. “Impairment of Emotional Memory and Ability to Identify Emotional States in Patients with Parkinson’s Disease.” Human Physiology 29, no. 6 (2003): 707-711. Sprengelmeyer, Young, Mahn, Schroeder, Woitalla, Buttner, Kuhn, and Przuntek. “Facial Expression Recognition in People with Medicated and Unmedicated Parkinson’s Disease.” Neuropsychologia 41 (2003): 1047-1057. Grande, Crosson, Heilman, Bauer, Kilduff, and McGlinchey. “Visual Selective Attention in Parkinson’s Disease: Dissociation of Exogenous and Endogenous Inhibition.” Neuropsychology 20, no. 3 (2006): 370-382. Dagher, Owen, Boecker, and Brooks. “The Role of the Striatum and Hippocampus in Planning: A PET Activation Study in Parkinson’s Disease.” Brain 124 (2001): 1020-1032. Kensinger, Shearer, Locascio, Growdon, and Corkin. “Working Memory in Mild Alzheimer’s Disease and Early Parkinson’s Disease.” Neuropsychology 17, no. 2 (2003): 230-239. Sagar, Sullivan, Gabrieli, Corkin, and Growdon. “Temporal Ordering and Short-term Memory Deficits in Parkinson’s Disease.” Brain 111 (1988): 525-539. Owen, James, Leigh, Summers, Marsden, Quinn, Lange, and Robbins. “Fronto-striatal Cognitive Deficits at Different Stages of Parkinson’s Disease.” Brain 115 (1992): 1727-1751. Brown, and Marsden. “Cognitive Function in Parkinson’s Disease: From Description to Theory.” Trends in Neurosciences 13, no. 1 (1990): 21-29. Cooper, Sagar, and Sullivan. “Short-term Memory and Temporal Ordering in Early Parkinson’s Disease: Effects of Disease Chronicity and Medication.” Neuropsychologia 13, no. 9 (1993): 933-949. Sahakian, Morris, Evenden, Heald, Levy, and Robbins. “A Comparative Study of Visuospatial Memory and Learning in Alzheimer-type Dementia and Parkinson’s Disease.” Brain 111 (1988): 695-718. Yonelinas, Otten, Shaw, and Rugg. “Separating the Brain Regions Involved in Recollection and Familiarity in Recognition Memory.” Journal of Neuroscience 25, no. 11 (2005): 3002-3008. Yonelinas, Kroll, Dobbins, Lazzara, and Knight. “Recollection and Familiarity Deficits in Amnesia: Convergence of Remember/Know, Process Dissociation, and Receiver Operating Characteristic Data.” Neuropsychology 12 (1998): 1-17. Mahieux, Fenelon, Flahault, Manifacier, Michelet, and Boller. “Neuropsychological Prediction of Dementia in Parkinson’s Disease.” Journal of Neurology, Neurosurgery and Psychiatry 64 (1998): 178-183. Norman. “Differential Effects of List Strength on Recollection and Familiarity.” Journal of Experimental Psychology Learning, Memory, and Cognition 28, no. 6 (2002): 1083-1094. Lees, and Smith. “Cognitive Deficits in the Early Stages of Parkinson’s Disease.” Brain 106, no. 2 (1983): 257-270. Davidson, Anaki, Saint-Cyr, Chow, and Moscovitch. “Exploring the Recognition Memory Deficit in Parkinson’s Disease: Estimates of Recollection versus Familiarity.” Brain 129 (2006): 1768-1779. Whittington, Podd, and Stewart-Williams. “Memory Deficits in Parkinson’s Disease.” Journal of Clinical and Experimental Neuropsychology 28 (2006): 738-754. Whittington, and Kan. “Recognition Memory Impairment in Parkinson’s Disease: Power and Meta-analyses.” Neuropsychology 14 (2000): 233-246.