HST.035 | Spring 2003 | Graduate

Principle and Practice of Human Pathology

Calendar

SES # TOPICS KEY DATES
1 Introduction to Human Pathology and Diagnostic Medicine (1 hr.) - Dr. Badizadegan

Lab: Cells and Tissues – Part 1 (2 hrs.)

Homework 1 out
2 Cytoskeleton and the Extracellular Matrix: “Scaffoldings of Life” (1 hr.) - Dr. Ingber

Epithelial Structure and Function (1 hr.) - Dr. Badizadegan

The Immune System (1 hr.) - Dr. Badizadegan

3 Cell Injury, Adaptation and Death (1 hr.) - Dr. Badizadegan

Lab: Cells and Tissues – Part 2 (2 hrs.)

Homework 1 due
4 Acute and Chronic Inflammation (1 hr.) - Dr. Badizadegan

Tissue Repair, Fibrosis and Healing (1 hr.) - Dr. Badizadegan

Diseases of Immunity (1 hr.) - Dr. Mitchell

5 Infectious Diseases: “The Biological Conflict of Interest” (1 hr.) - Dr. Badizadegan

Lab: Infection and Immunity (2 hrs.)

6 Transplantation: “Friendly Organs in a Hostile Environment” (1 hr.) - Dr. Colvin

Tissue Engineering and Organ Fabrication: “Medical Rationale and Engineering Challenges” (1 hr.)

Minicases (1 hr.) - Dr. Badizadegan

Homework 2 out
7 Host Response to Artificial Materials and Implanted Devices (1 hr.) - Dr. Schoen

Lab: Transplantation and Biomaterials (2 hrs.)

8 Introduction to Organ Systems Pathology (1 hr.) - Dr. Badizadegan

Are We What We Eat? “The Link Between Diet and Disease Development” (1 hr.) - Dr. Hu

Environmental Exposure: “Is It Making You Sick?” (1 hr.) - Dr. Dockery

9 Cardiomyopathies: “Many Roads to a Broken Heart” (1 hr.) - Dr. Seidman

Lab: The Heart (2 hrs.)

Homework 2 due
10 Vascular Pathobiology: “Endothelium as Nature’s Blood Container” (1.5 hrs.) - Dr. Gimbrone

Minicases (0.5 hrs.) - Dr. Badizadegan

Ischemia and Infarction (1 hr.) - Dr. Badizadegan

11 Patterns and Consequences of Glomerular Damage (1 hr.) - Dr. Rennke

Lab: Kidneys and Blood Vessels (2 hrs.)

Homework 3 due

Homework 4 out

12 Genetic Disorders (1 hr.) - Dr. Badizadegan

Minicases (0.5 hrs.) - Dr. Badizadegan

Diseases of the Lung (1.5 hrs.)

13 The Liver (1 hr.) - Dr. Badizadegan

Lab: Lungs and Liver (2 hrs.)

14 Gastrointestinal Disorders: “Guts with No Glory!” (2 hrs.) - Dr. Badizadegan

Genetic Progression in Gastrointestinal Neoplasia (1 hr.) - Dr. Redston

Homework 4 due

Homework 5 out

15 Cervical Neoplasia: “Lessons from Viral Oncogenesis” (1 hr.) - Dr. Crum

Lab: The Gastrointestinal Tract (2 hrs.)

Homework 5 due
16 Mid-Term Exam (1 hr.)

Feedback Session and Review of the Mid-Term Exam (1 hr.)

Lymphoid Neoplasms (1 hr.) - Dr. Aster

17 Sickle Cell Disease: “From Membrane Pathophysiology to Membrane-Targeted Therapy” (1 hr.) - Dr. Brugnara

Lab: Red and White Blood Cells (2 hrs.)

Homework 6 out
18 Introduction to the Nervous System (1 hr.)

Toxic Proteins and Neurodegenerative Diseases (1 hr.) - Dr. Feany

CNS Neoplasia (1 hr.) - Dr. Louis

19 Diseases of Skeletal Muscle (1 hr.) - Dr. Lidov

Lab: The Nervous System (2 hrs.)

20 Surgical Pathology and Other Gold Standards (1 hr.) - Dr. Badizadegan

Molecular and Cytogenetic Analyses in Diagnostic Pathology (1 hr.) - Dr. Fletcher

DNA Microarrays in Cancer Diagnosis and Management (1 hr.) - Dr. Golub

Homework 6 due
21 Bioinformatics in Pathology: “Can any Useful Information be Extracted from all this Data?” (1 hr.)

Functional Imaging (1 hr.) - Dr. Rosen

Molecular Imaging (1 hr.)

22 Lab: The Clinical Laboratories (Medical Area) (3 hrs.) Homework 7 due
23 Optical Coherence Tomography: “Shedding Light on Human Disease” (1 hr.) - Dr. Tearney

Optical Spectroscopy: “Diagnosis in a Flash!” (1 hr.) - Dr. Feld

Transfer of Healthcare Technologies: “How to Make New Diagnostic Technologies a Clinical Reality?” (1 hr.) - Dr. Murray

24 Student Presentations (3 hrs.)

25 Student Presentations (3 hrs.)

26 Autopsy: “The Final Answer?” (Medical Area) (1 hr.) - Dr. Badizadegan

Lab: Autopsy Conference (Medical Area) (2 hrs.)

27 Pathology and the Law (1 hr.) - Dr. Bieber

Minicases (1 hr.) - Dr. Badizadegan

Human Pathology: “Past, Present, and the Future” (1 hr.) - Panel Discussion

28 Final Exam

Course Info

As Taught In
Spring 2003
Level
Learning Resource Types
Lecture Notes