HST.151 | Spring 2005 | Graduate

Principles of Pharmacology

Study Materials

Clinical Pharmacology in the Operating Room (PDF)

Exam Reviews

Midterm Exam

Review (PDF)

Drug List (PDF)

Final Exam

Review (PDF 1 - 1.3 MB) (PDF 2)

Drug List (PDF)

2004 Midterm Exam Review (PDF)

Useful References

Tallarida, R. J., and L. S. Jacob. The Dose-Response Relation in Pharmacology. New York, NY: Springer-Verlag, 1979. ISBN: 9780387904153.
A slim volume that deals in some depth with the quantitative aspects of dose-response relationships.

Physicians Desk Reference. 60th ed. Montvale, NJ: Thomson Healthcare, 2005.ISBN: 9781563635274.
The “PDR.” A compendium of FDA-approved package inserts updated annually and available on most medical wards. Written by drug companies and edited by lawyers and bureaucrats. Readily available information on approved indications and dosages, strengths and dosage forms available, pill shape and color, major side effects and precautions.

Pratt, W. B., and P. Taylor, eds. Principles of Drug Action: The Basis of Pharmacology. 3rd ed. New York, NY: Churchill-Livingstone. 1990. ISBN: 9780443086762.
A rigorous book with in-depth discussions of the principles underlying general pharmacology.

Thomson Healthcare, Inc., ed. Drug Information for the Health Care Professional. 25th ed. Vol. 1. United States Pharmacopeial Convention, Micromedex, Inc., 2005. ISBN: 9781563635144.
A huge collection of monographs on drug classes and individual drugs updated annually. Cumbersome presentation, but includes information on unapproved indications and reflects actual practice better than PDR. Also available on CD-ROM.

USP Dictionary of USAN (United States Adopted Names) and International Drug Names. Rockville, MD: United States Pharmacopeial Convention, 2002. ISBN: 9781889788111.
Listing of approved and investigational drugs with manufacturer’s code, Adopted (trivial) name, mol. wt., and structural formula.

Kenakin, T. Pharmacologic Analysis of Drug-Receptor Interaction. 2nd ed. New York, NY: Raven Press, 1993. ISBN: 9780781700658.
Treatise on theoretical and quantitative aspects of drug-receptor interaction. Detailed treatment of antagonists, partial agonists, radioligand binding, etc.

Gibaldi, M., and D. Perrier. Pharmacokinetics. 2nd ed. New York, NY: Marcel Dekker, 1982. ISBN: 9780824710422 .
“Classic” pharmacokinetics. Still a useful book after all these years.

Carruthers, et. al., eds. Melmon and Morrelli’s Clinical Pharmacology. 4th ed. New York, NY: McGraw-Hill, 2000. ISBN: 9780071054065 .
Pharmacology from the perspective of clinical therapeutics. Lengthy, up-to-date chapters are not especially easy to use for quick reference, but the book contains hundreds of useful “pearls” about approaches to patients and drug therapy of most disease states.

Selected Periodicals

  1. Annual Review of Pharmacology and Toxicology: In-depth reviews of selected topics.
  2. Clinical Pharmacology and Therapeutics
  3. Drug Metabolism and Disposition
  4. Molecular Pharmacology
  5. Journal of Pharmacology and Experimental Therapeutics
  6. Pharmacological Reviews
  7. Molecular Interventions: Periodicals 2-7 are authoritative, official journals of the American Society for Pharmacology and Experimental Therapeutics (ASPET). No. 7 is a recent addition - short, up-to-date reviews with excellent graphics.
  8. The Medical Letter on Drugs and Therapeutics: Popular bi-weekly newsletter announcing new drugs and giving summaries of recommended drug treatment for specific clinical applications. Includes comparative cost data. Brief reviews are authoritative, but without references.
  9. Trends in Pharmacological Sciences: For the receptor afficionado. If you really want to know the latest nomenclature and selective ligands for every defined receptor subtype, you’ll find the information here. Good articles (mainly review) but tend toward the heavily theoretical.

Course Info

Learning Resource Types
Exams with Solutions
Lecture Notes
Presentation Assignments with Examples
Problem Sets with Solutions
Written Assignments