A selection of downloadable lecture notes from both the Fall 2005 and Fall 2002 versions of this course are available below:
Fall 2005
| SES # | TOPICS |
|---|---|
| 1 | Overview - Dr. Shiv Pillai |
| 2 | Cells of the Immune System - Dr. Shiv Pillai (PDF) |
| 3 | Lymphocyte Homing - Dr. Ulrich von Andrian (PDF) |
| 4 | Case Presentations at MGH |
| 5 |
Antibodies and Antigens - Dr. Shiv Pillai (PDF)
Analyzing a Clinical Case - Dr. Bobby Cherayil |
| 6 | Antigen Receptors and the Generation of Diversity - Dr. Shiv Pillai (PDF) |
| 7 | Case Presentations at MGH |
| 8 | B Lymphocyte Development and Activation - Dr. Shiv Pillai (PDF) |
| 9 |
Tutorial Session I
Antibody Dependent Protection - Dr. Shiv Pillai |
| 10 | Antigen Presentation - Dr. Hidde Ploegh (PDF) |
| 11 |
Tutorial Session II
T Lymphocyte Development - Dr. Shiv Pillai (PDF) |
| 12 |
Tutorial Session III
Signal Transduction in Lymphocytes I - Dr. Shiv Pillai |
| 13 | Cell Mediated Immunity - Dr. Andrew Lichtman (PDF) |
| 14 |
Tutorial Session IV
Signal Transduction in Lymphocytes II - Dr. Shiv Pillai |
| 15 | Paper Discussion 1 |
| Midterm Exam | |
| 16 |
Dendritic Cells - Dr. Shannon Turley
Frontiers: Costimulation - Dr. Arlene Sharpe (PDF) |
| 17 | Paper Discussion 2 |
| 18 |
Memory and Death - Dr. Shiv Pillai (PDF)
Immunology of TB - Dr. Samuel M. Behar |
| 19 |
Tutorial Session V
Immune Mediated Injury - Dr. Richard Mitchell |
| 20 |
Asthma and Allergy - Dr. Dale T. Umetsu
Frontiers: DC and Innate Immunity - Dr. Nir Harcohen |
| 21 |
Multiple Sclerosis - Dr. David Hafler
Frontiers: Autoimmune TCRs - Dr. Kai Wucherpfennig |
| 22 | Paper Discussion 3 |
| 23 |
Leukemias and Lymphomas - Dr. Jon C. Aster
CD1 and Lipid Antigens - Dr. Richard S. Blumberg |
| 24 |
Tutorial Session VI
Transplantation Immunology - Dr. Hugh Auchincloss |
| 25 |
Immunology of HIV/AIDS - Dr. Bruce Walker
Frontiers: Genetic Instability and Cancer - Dr. Frederick W. Alt |
| 26 |
Regulatory T Cells - Dr. Diane Mathis
Bone Marrow Transplant - Dr. Megan Sykes |
| 27 |
Tutorial Session VII
Tumor Immunology - Dr. Andrew Lichtman (PDF) |
| 28 | Paper Discussion 4 |
| 29 |
Regulating Humoral Autoimmunity - Dr. Shiv Pillai
Inflammatory Bowel Disease - Dr. Ramnik Xavier |
| 30 | Immunodeficiency Disorders - Dr. Francisco Bonilla |
| 31 | RA and Lupus - Dr. Paul Anderson |
| 32 | Genetic Susceptibility to Disease - Dr. Shiv Pillai (PDF) |
| Final Exam |
Fall 2002
| TOPICS | NOTES |
|---|---|
| Overview |
Lecture Notes (PDF)
Handout (PDF) |
| Cells of Immune System and Innate Immunity |
Lecture Notes (PDF)
Handout (PDF) |
|
Antibodies
Antibody-dependent Protection Mechanisms |
Lecture Notes (PDF) and (PDF) |
|
Antigen Receptors and Development of Diversity
T Lymphocyte Development |
Handout (for Antigen Receptors) (PDF)
Handout (for T Lymphocyte Development) (PDF) |
| B Lymphocyte Dev and Activation | Handout (PDF) |
| Cell-mediated Immunity | Handout (PDF) |
| Lymphocyte Homing | Lecture Notes (PDF) |
| MHC/Antigen Presentation | Lecture Notes (PDF) |
|
A Bloody Glove - Tutorial
Lymphocyte Activation, Cytokines, Costim |
Handout (PDF) |
|
Transplantation Immunology
Presentations 7 and 8: Chronic Granulomatous/MS |
Lecture Notes (PDF) |
| Immunology of HIV Disease | Lecture Notes (PDF) |
|
Costimulation
Presentation 9: Lymphoprolif Syndrome |
Lecture Notes (PDF) |
|
Memory and Death in Immune System
IgE System and Immediate Type Hypersens |
Lecture Notes (PDF)
Handout (PDF) |
| Tumor Immunity | Handout (PDF) |
| Immunodeficiency Syndromes/Review | Lecture Notes (PDF) |