HST.121 | Fall 2005 | Graduate



Student Seminars

Student Seminar Topics

Seminar 1: The Alimentary Tract

Mucosal barrier

  • General topics
  • Tight junctions
  • The glycocalyx
  • Mucosa-Associated Lymphoid Tissue
  • M-cells
    Molecular biology of colorectal carcinogenesis
    DNA mismatch repair genes and cancer
    Chemical, radiation, and drug-induced mucosal damage
    Microbial pathogenesis in the GI tract
    • Shigella
    • Sahnonella
    • E. Coli
    • H. pylori

Seminar 2: The Pancreatobiliary Tracts

Biology and physical chemistry of bile and bile salts
Structure and function of biological membranes
Mechanisms of hereditary and acquired pancreatic disease

  • Acute and chronic pancreatitis
  • Cystic Fibrosis
  • Shwachman-Diamond syndrome
    Gallstone disease
  • Genetics
  • Biochemistry

Seminar 3: The Liver

Mechanisms of liver detoxification

  • Microsomal enzymes
  • Drug-induced liver disease
    Immunology of the liver
  • Viral hepatitis
  • Autoimmune liver disease
    Mechanisms of acute and chronic liver damage
  • Alcoholic liver disease
  • Fibrosis and cirrhosis
    Inherited/metabolic disorders of the liver
  • Alphal-antitrypsin deficiency
  • Tangier disease
  • Glycogen storage disease
  • Mucopolysaccharoidosis
  • Lysosomal storage disease