Biomedical Devices Design Laboratory

Syllabus

Course Meeting Times

Lectures: 2 sessions / week, 1.5 hours / session

Labs: 1 session / week, 3 hours / session

Course Description

This course provides intensive coverage of the theory and practice of electromechanical instrument design with application to biomedical devices. Students will work with MGH doctors to develop new medical products from concept to prototype development and testing. Lectures will present techniques for designing electronic circuits as part of complete sensor systems. Topics covered include: basic electronics circuits, principles of accuracy, op amp circuits, analog signal conditioning, power supplies, microprocessors, wireless communications, sensors, and sensor interface circuits. Labs will cover practical printed circuit board (PCB) design including component selection, PCB layout, assembly, and planning and budgeting for large projects. Problem sets and labs in the first six Weeks are in support of the project. Major team-based design, build, and test project in the last six Weeks. Student teams will be composed of both electrical engineering and mechanical engineering students.

Teaching Staff

Instructor: Dr. Hongshen Ma
Course Administrator: Maureen Lynch
Mechanical Guru: Prof. Alexander H. Slocum
Electrical Guru: Dr. Chris Salthouse
Medical Guru: Dr. Rajiv Gupta

Grading

ACTIVITIES	PERCENTAGES
Assignments and labs	40%
Team project	60%

Assignments and Labs

There will be three assignments covering these lecture areas:

• Assignment 1: Impedance analysis
• Assignment 2: OpAmp circuits
• Assignment 3: Sensors and signal processing

There will be one lab designed to lead students through the process of designing, fabricating, and assembling a printed circuit board (PCB). Students will create a multipurpose data acquisition system that includes a microprocessor, USB connectivity, and wireless connectivity. The labs are done individually, which means that each student will have the opportunity to make their own PCB. The PCB created in the lab will be useful in the project. The lab will require approximately half of the semester to complete and will be composed of the following 6 parts:

• Lab 1: Circuit design and component selection
• Lab 2: Learn to use PCB Artist, generate libraries, create schematic
• Lab 3: PCB layout
• Lab 4: PCB assembly
• Lab 5: Microprocessor programming
• Lab 6: PC user interface design using Visual Basic® (optional)

Team Project

Students will attend a special lecture two days before Lec #2, where doctors from MGH will present their problems and needs for new medical devices. Students will self-organize into teams of four and each team will select a particular problem on which they would like to work. An approximate schedule for the project is given in the course schedule. Starting in Week 3, the teams will meet weekly with staff. Each sponsoring doctor will also be available to meet with the team on a weekly basis. From Week 7 onwards, each team will make weekly presentations on their progress. There will also be a final presentation and demonstration of their device to the MGH doctors in the last Week. A detailed write-up of the project results in the format of a journal article (20 pages double spaced plus figures. Details go in Appendices) is required. An “A” grade project is one that is presented in form and content that is ready to be submitted to a peer-reviewed journal.

Each team will have a budget of $3000 to prototype and test their solution. Legitimate expenses include mechanical and electronic components, PCB fabrication, machine shop and rapid prototyping services (must get an estimate for cost of job), local travel (mileage), etc. (ask Maureen Lynch, Hong Ma, or Prof. Slocum if in doubt). Maureen Lynch will administer team accounts. There is lab space set aside for each team in 5-007.

A key part of your project is to record what you did to help you organize your thoughts and also allow others (or yourself) to continue the work after the semester. Therefore, it is critical to write-as-you-go. Otherwise, brilliant ideas will be lost and may never be reformulated again.

Calendar

WEEK #	TOPICS	KEY DATES
1	Lab 1 and 2 distributed
	Lecture 1 - Introduction
2	Doctors present ideas in class Lab 1 and 2 Design custom circuit, learn PCB artist, generate libraries, create schematic	Project goals Students form teams of 4
	Lecture 2 - Basic electronics Linear elements, thevenin-norton, impedance analysis
3	Lecture 3 - Diodes and transistors Models, LEDs, peak-detector, zeners, diode protection circuits, BJT, FET, amplifiers, drivers, H-bridges Lab 3 Layout PCB	Lab 1 and 2 due Project goals Define functional requirements Define components of the system Research strategies by literature and patent review
	Lecture 4 - Power supplies Proper bypassing, linear power supplies, switching power supplies MIT libraries lectures on literature and patent searching	Lab 3 due; submit PCB for manufacturing
4	Lecture 5 - Microprocessors I Basic topologies, feedback, stability, accurate peak detector	Project goals Identify most critical module (MCM) Develop bench level experiments to test strategies for the MCM Begin to acquire components for MCM and other modules
5	Lecture 6 - Microprocessors II Practical considerations, reading op amp datasheets error propagation, filters Lab 4 Soldering, assembly, and debugging	Project goals Run bench level experiments
	Lecture 7 - OpAmps I Basics programming concepts, memory organization, clocks, ADCs	Lab 4 due
6	Lab 5 Microprocessor programming	Project goals Design circuits for MCM
	Robopsy guest lecture
7	Lecture 8 - OpAmps II Timers, communications, wireless	Project goals Design circuits for other modules Layout circuits Submit for manufacturing
	Lecture 9 - Analog signal processing ADC, references, noise, synchronous detection	Lab 5 due
8	Lecture 10 - Sensors I Capacitive, impedance, optical Lab 6 (optional) PC user interface design in Visual Basic®	Project goals Assemble and test first iteration
	Lecture 11 - Sensors II Encoders, magnetic, strain acoustic, inertial	Lab 6 due
9	Chris Salthouse guest lecture	Project goals Assemble and test first iteration
	No lecture, weekly team meeting with staff
10	No lecture, weekly team meeting with staff	Project goals Design circuits for 2nd iteration
11	No lecture, weekly team meeting with staff	Project goals Submit for final manufacturing
12	No lecture, weekly team meeting with staff	Project goals Develop software and firmware
13	No lecture, weekly team meeting with staff	Project goals Integration and test device
14	No lecture, weekly team meeting with staff	Project goals Prototype complete, final paper done
	Final presentations in class: projects 1 and 2
15	Final presentations in class: projects 3 and 4
	Final class: turn in journal article as final paper Recap and reflections	Final papers will be accepted as late as last class