20.201 | Fall 2013 | Graduate

Mechanisms of Drug Actions

Lecture and Recitation Slides

Session Key

L = Lecture

R = Recitation

Lecturer Key

PD = Prof. Peter Dedon

MM = Dr. Mark Murcko

ST = Prof. Steven Tannenbaum

  CK = Dr. Charles Knutson

  TA = Teaching assistants

Overview of the Drug Discovery Process; Fundamental Principles
L1 Introduction and Fundamentals (PDF) PD, MM, ST
L2 Overview of Drug Development 1 (PDF - 12.6MB) MM
L3 Overview of Drug Development 2 (PDF - 9.0MB) MM
R1 Fundamentals (PDF - 1.9MB) PD

Biochemistry Review Exercise (PDF - 1.3MB)

Biochemistry Review Notes (PDF)

L5 Uptake and Distribution (Same slides as Recitation 1) PD
R2 Drug Metabolism 1 (PDF - 1.2MB) ST
L8 Drug Metabolism 2 (PDF - 2.3MB) ST
L11 Pharmacokinetics (PDF - 1.3MB) PD
Case Studies and Literature Discussions; Case Study Project
R5 Overview of Drug Development 3 (PDF - 12.5MB) MM
L13 Case Study (PDF - 7.7MB) MM
L14 Case Study: Antibiotics (PDF - 13.3MB) CK

Project Help Session

Review of Question 2 (PDF)

L22 Case Study: Cystic Fibrosis (PDF - 7.0MB) MM

Course Info

Learning Resource Types
Problem Sets with Solutions
Exams with Solutions
Lecture Notes
Projects with Examples
Written Assignments
Instructor Insights