Instructor Key RK = Roger Kamm AG = Alan Grodzinsky LEC # TOPICS & SLIDES INSTRUCTORS Molecular Mechanics 1 Length, Time, & Molecular-scale Forces in Biology (PDF - 1.6MB) RK 2 Single Molecule Mechanics (PDF) RK 3 Energy Landscapes and Transition States (PDF) RK 4 Mechanochemistry at the Molecular Scale (PDF - 3.7MB) AG 5 Kramers’ and Bell’s Models of Reversible Binding (PDF - 1.3MB) RK 6 Experimental Methods in Single Molecule Mechanics (PDF - 1.5MB) RK Tissue Mechanics 7 Composition of Extracellular Matrix Constituents of Tissues; Relevance to Elastic (Time-independent) Behavior of Tissues (PDF - 2.8MB) AG 8 Elastic (Time-independent) Behavior of Tissues (cont.) (PDF - 2.1MB) AG 9 Elastic (Time-independent) Behavior of Tissues (cont.) (PDF - 2.2MB) AG Time-dependent Tissue Behavior (Viscoelasticity and Poroelasticity) 10 Finish Topics on Tissue Elasticity; Begin Viscoelasticity (PDF - 1.8MB) AG 11 Time-dependent Viscoelasticity of Tissues (PDF - 2.2MB) AG 12 Dynamic (Frequency-dependent) Viscoelasticity (PDF - 1.7MB) AG 13 Poroelastic (Time-dependent) Behavior of Tissues (PDF - 2.3MB) AG 14 Poroelastic (Frequency-dependent) Behavior of Tissues (PDF - 1.8MB) AG 15 Dynamic Nanomechanical Behavior of Extracellular Matrix Macromolecules (PDF - 3.1MB) AG 16 Time- and Frequency-dependent Behavior of Intracellular Networks (PDF - 2.7MB) AG Cell Mechanics 17 Cell Mechanics: Structure of the Cell (PDF - 1.8MB) RK 18 Visco / Poroelasticity, Large Amplitude Deformations (PDF) RK 19 Microstructural Models of the Cytoskeleton (PDF) RK 20 The Cell Membrane (PDF) RK 21 Cell Motility and Mechanotransduction (PDF - 1.3MB) RK Capstone Problems 22 The Physics of Cancer (PDF - 3.4MB) RK Term Project Group Presentations Term Project Group Presentations (cont.) 23 Molecular Electromechanics: Electromechanical and Physicochemical Properties of Tissues (Lecture Slides are not available.) AG 24 Muscle from the Molecular, Cellular and Tissue Perspectives (Lecture Slides are not available.) RK