Biomaterials-Tissue Interactions

Lecture Notes

LEC #	TOPICS	INSTRUCTORS	LECTURE SLIDES
I. Tissue environment of the implanted biomaterial: unit cell processes
1	Survey of clinical cases of biomaterials-tissue interactions	Spector, Yannas	(PDF - 9.4MB) (PDF - 4.2MB)
2	Tissue structures and unit cell processes Integrins and adhesion proteins	Spector	(PDF - 1.2MB) (PDF - 3.0MB) (PDF) (PDF - 3.2MB)
3	Unit cell processes comprising the healing response	Spector	(PDF - 4.0MB) (PDF - 4.3MB)
4	Unit cell processes underlying tissue engineering	Spector	(PDF - 7.5MB)
5	Structure and function of naturally occurring ECMs	Yannas	(PDF) (PDF)
6	ECM does not regenerate spontaneously	Yannas	(PDF)
7	Quiz 1
II. Cell-surface interactions
8	Analysis of surfaces of biomaterials and protein adsorption	Spector	(PDF - 1.7MB)
9	Phenotype changes following adhesion on biomaterials	Yannas	(PDF)
10	Structural determinants of biologically active materials	Yannas	(PDF - 2.2MB)
11	Methodology for cell-surface interactions	Yannas	(PDF)
12	Cell-scaffold interactions during regeneration	Yannas	(PDF - 3.8MB)
13	Noncooperative cell-surface interactions	Yannas	(PDF - 3.7MB)
14	From randomness to cooperativity	Yannas	(PDF)
15	Quiz 2
III. In vivo and clinical case studies
16	Tissue response to implants; biocompatibility	Spector	(PDF - 6.1MB)
17	Epithelialization (epidermal regeneration) and endothelialization of vascular prostheses	Spector	(PDF - 1.2MB) (PDF)
18	In vivo synthesis of skin	Yannas	(PDF - 1.7MB) (PDF)
19	In vivo synthesis of peripheral nerve	Yannas	(PDF - 3.9MB)
20	Rules for synthesis of tissues and organs	Yannas	(PDF - 2.8MB)
21	Joints and dental tissues: prosthetic replacement	Spector	(PDF - 7.7MB) (PDF - 9.9MB)
22	Implants for bone regeneration	Spector	(PDF - 4.0MB)
23	Regeneration of soft musculoskeletal tissues	Spector	File not available
24	Biomaterial applications in the heart and other organs	Spector	(PDF - 3.7MB)
25	Quiz 3