Readings

Required Text

[MHS] = Mohrig, Alberg, et al. Laboratory Techniques in Organic Chemistry. 4th ed. W. H. Freeman, 2014. ISBN: 9781464134227.

[SWH] = Skoog, West, et al. Fundamentals of Analytical Chemistry. 9th ed. Brooks Cole, 2013. ISBN: 9780495558286. [Preview with Google Books]

[S&L] = Skoog, Holler, and Crouch. Principles of Instrumental Analysis. 6th ed. CL, 2007. ISBN: 9788131525579.

[Oxtoby] = Gillis, and Campion. Principles of Modern Chemistry. 7th ed. Cengage Learning, 2012. ISBN: 9780840049315.

[Atkins] = Jones, and Laverman. Chemical Principles: The Quest for Insight. 6th ed. W. H. Freeman, 2012. ISBN: 9781429288972.

[SFH] = Steinfeld, Joesph S. Francisco, and Wiliam L. Hase. Chemical Kinetics and Dynamics. 2nd ed. Pearson, 1998. ISBN: 9780137371235.

[JWZ] = Zubrick. The Organic Chem Lab Survival Manual: A Student’s Guide to Techniques. 10th ed. Wiley, 2016. ISBN: 9781118875780.

[C&G] = Coghill, and Garson, eds. The ACS Style Guide: Effective Communication of Science Information. 3rd ed. American Chemical Society, 2006. ISBN: 9780841239999.

TOPICS READINGS
Introduction

Lab Manual: Sections I, II, III, and Experiment 2 (Ellen Swallow Richards Lab)

[MHS] Chapter 1: Safety, pp. 3–21.

[MHS] Chapter 3: Laboratory Notebook, pp. 32–39.

[MHS] Chapter 4: Laboratory Glassware, pp. 44–51.

[MHS] Chapter 5: Measuring Mass and Volume & Transfers, pp. 52–72.

[MHS] Chapter 6: Heating Methods & Cooling Methods, pp. 73–86.

[MHS] Chapter 13: Using the Literature of Organic Chemistry, pp. 501–506.

[SWH] “Balances.” pp. 23–30 (pp. 797–806).

Optional

[JWZ] Chapter 13: Buchner Funnels and Filtration, pp. 107–113.

Ellen Swallow Richards Lab

[MHS] Chapter 5: Measuring Mass and Volume, pp. 52–64.

[SWH] Chapter 20: Standard Reducing Agents, Thiosulfate Solutions, pp. 511–514.

[SWH] Chapter 23: Dissolved Oxygen, pp. 681–682.

[SWH] “Phosphate Ion Determination FIA.” pp. 1059–1061.

[MHS] Chapter 25: UV & VIS Spectroscopy, pp. 465–475.

Michaud, Joy. Chapter 4 in A Citizens Guide to Understanding and Monitoring Lakes and Streams (PDF – 7.4MB). Puget Sound Water Quality Authority, 1991, pp. 45–58. 

Review

[Oxtoby] Chapter 20.1–20.2: General Aspects of Molecular Spectroscopy.

[Oxtoby] Chapter 20.5: Excited Electronic States.

[Oxtoby] Chapter 8.5: The Spectrochemical Series.

OR

[Atkins] Chapter: 4.12: Orbitals in Polyatomic Molecules, pp. 139–140.

[Atkins] Chapter: 17.8: The Electronic Structures of Complexes, pp. 749–759.

Read

[SWH] Chapter: 26: Molecular Absorption Spectroscopy, pp. 723–759.

Optional

[SWH] Chapter: 25: Instruments for Optical Spectroscopy.

OR

[S&L] Chapter 6: Intro to Spectrometric Methods, pp. 132–135, 141–144, and 157–159.

[S&L] Chapter 14: Application of UV/VIS spectroscopy, pp. 367–374.

Optional

[S&L] Chapter 8: Instruments for Optical Spectroscopy, pp. 215–228.

Error Analysis

[MHS] Chapter 5.5: Measurement Uncertainty & Error Analysis, pp. 64–73.

[SWH] Chapter 5: Errors in Chemical Analysis.

[SWH] Chapter 6: Random Errors in Chemical Analysis.

[SWH] Chapter 7: Statistical Evaluation of Data.

OR

[S&L] Appendix 1: Evaluation of Analytical Data, pp. 967–993.

Writing Reports [C&G] The ACS Style Guide.

Ferrocene Lab

  • Chromatography

Lab Manual: Experiment 1 (Ferrocene).

[MHS] Chapter 12: Boiling Point & Distillation, pp. 173–205.

[MHS] Chapter 6: Heating & Cooling Methods, pp .73–86.

[MHS] Chapter 7: Setting Up Organic Reactions, pp. 87–106.

[MHS] Chapter 16: Sublimation, pp. 236–239.

[MHS] Chapter 5: Transfer of Reagents Using a Syringe, pp. 59–61.

[Oxtoby] Chapter 10.6: Phase Diagrams, pp. 462–465.

OR

[Atkins] Chapter 10.6: Phase Diagrams, pp. 375–378.

[MHS] Chapter 18: Thin-Layer Chromatography, pp. 255–267.

[MHS] Chapter 19: Liquid chromatography, pp. 270–291.

[Oxtoby] Chapter 14.8: Distribution of a Single Species between Immiscible Phases: Extraction and Separation Processes, pp. 650–654.

OR

[Atkins] Major Technique 4 Chromatography F59.

Essential Oils Lab

  • Infrared Spectroscopy
  • Chromatography
  • Refractometry/Polarimetry

Lab Manual: Experiment 3 (Essential Oils)

[MHS] Chapter 12: Boiling Points and Distillation, pp. 173–205.

[Oxtoby] Chapter 11.6: Mixtures and Distillation, pp. 499–504.

OR

[Atkins] Chapter 10.15: Vapor Pressure Lowering, pp. 392–394.

[Atkins] “Binary Liquid Mixtures.” pp. 402–440.

[MHS] Chapter 21: Infrared Spectroscopy, pp. 311–344.

[Oxtoby] Chapter 20.3: Vibrations and Rotations of Molecules.

OR

[Atkins] “Major Technique 1 Infrared Spectroscopy.” pp. 105–106.

Optional

[S&L] Chapter 12: Infrared Absorption Spectroscopy.

[MHS] Chapter 20: Gas Chromatography, pp. 291–308.

[MHS] Chapter 13: Refractometry, pp. 206–211.

[MHS] Chapter 17: Optical Activity and Polarimetry, pp. 240–251.

[Atkins] Box 17.2 and Figure 16.25 Optical activity, Plane polarized light, p. 746.

Fischer Esterification Lab

  • Refluxing
  • NMR
  • Mass Spectroscopy
  • Infrared Spectroscopy

Lab Manual: Experiment 4 (Fischer Esterification)

[MHS] Chapter 5: Measuring Mass & Volume, Using Pasteur Pipettes, Thermometer Calibration, pp. 52–63.

[MHS] Chapter 7: Refluxing a Reaction Mixture, pp. 59–60.

[MHS] Chapter 11: Extraction: Separatory Funnel, pp. 113–124.

[MHS] Chapter 12: Boiling Point & Distillation, pp. 174–176.

[MHS] Chapter 13: Refractive Index, pp. 206–211.

[MHS] Chapter 21: Infrared Spectroscopy, pp. 311–344.

[MHS] Chapter 22: Nuclear Magnetic Resonance, pp. 350–405.

[MHS] Chapter 24: Mass Spectrometry, pp. 441–462.

[Atkins] Chapter 10: Distillation, pp. 404–406.

[Atkins] Chapter 10.3: Clausius-Clapeyron Equation, pp. 371–373.

[Atkins] Chapter 10.4: Boiling, pp. 373–374.

[Atkins] Chapter 20: Esters, pp. 828–829.

Catalase Kinetics Lab

Lab Manual: Experiment 5 (Catalase Kinetics)

[SFH] “Definition of the Rate of a Chemical Reaction.” pp. 1–3.

[SFH] “Order and Molecularity of a Reaction.” pp. 3–6.

[SFH] “Reaction Mechanisms.” pp. 17–18.

[SFH] “Enzyme-Catalyzed Reactions.” pp. 159–163.

[MHS] “Measuring Mass and Volume.” pp. 52–61.

[MHS] “Heating and Cooling Methods.” pp. 73–86.

[SWH] “Rates of Chemical Reaction.” pp. 879–884.

[SWH] “Enzyme-Catalyzed Reactions.” pp. 885–892.

[MHS] Chapter 25: UV & VIS Spectroscopy, pp. 465–487.

OR

[Atkins] Chapter 4.12: Orbitals in Polyatomic Molecules, pp. 139–140.

[Atkins] Chapter 17.8: The Electronic Structures of Complexes, pp. 749–759.

Read

[SWH] Chapter 26: Molecular Absorption Spectroscopy, pp. 723–759.

Optional

[SWH] Chapter 25: Instruments for Optical Spectroscopy.

OR

[S&L] Chapter 6: Intro to Spectrometric Methods, pp. 132–135, 141–144, and 157–159.

[S&L] Chapter 14: Application of UV/VIS spectroscopy, pp. 367–374.

Optional

[S&L] Chapter 8: Instruments for Optical Spectroscopy, pp. 215–228.

Course Info

Learning Resource Types

theaters Lecture Videos