LEC # | TOPICS | KEY DATES |
---|---|---|
1 | Welcome; Introduction and course organization | |
2 | Chemical bonding and molecular interactions; Lipids and membranes | |
3 | Structures of amino acids, peptides and proteins | |
4 | Enzymes and metabolism | |
5 | Carbohydrates and glycoproteins | Problem set 1 due |
6 | Nucleic acids | |
7 | Replication | |
8 | Transcription | |
9 | Chromatin remodeling and splicing | |
10 | Translation | Problem set 2 due |
11 | Cells, the simplest functional units | |
Exam 1 (Covering Lectures 1–10) | ||
12 | Genetics 1—Cell division and segregating genetic material | |
13 | Genetics 2—Rules of inheritance | |
14 | Genetics 3—Linkage, crossing over | Problem set 3 due |
15 | Genetics 4—The power of model organisms in biological discovery | |
16 | Recombinant DNA, cloning, and editing | |
17 | Genomes and DNA sequencing | |
18 | SNPs and human genetics | Problem set 4 due |
Exam 2 (Covering Lectures 11–17) | ||
19 | Cell trafficking and protein localization | |
20 | Cell signaling 1—Overview | |
21 | Cell signaling 2—Examples | |
22 | Neurons, action potential, and optogenetics | |
23 | Cell cycle and checkpoints | |
24 | Stem cells, apoptosis, and tissue homeostasis | |
25 | Cancer 1 | Problem set 5 due |
26 | Cancer 2 | |
Exam 3 (Covering Lectures 18–25) | ||
27 | Visualizing life—Dyes and stains | |
28 | Visualizing life—Fluorescent proteins | |
29 | Cell imaging techniques | |
30 | Immunology 1—Diversity, specificity, and B cells | |
31 | Immunology 2—Memory, T cells, and autoimmunity | News brief proposal due |
32 | Infectious disease, viruses, and bacteria | |
33 | Bacteria and antibiotic resistance | |
34 | Viruses and anti-viral resistance | Problem set due |
35 | Reproductive cloning and embryonic stem cells | |
36 | “In the news” | |
Final Exam (Covering Lectures 1–36) |
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Fall
2018
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