All readings are from the required course textbook:
Sadava, D. E., D. M. Hillis, et al. Life: The Science of Biology. 11th ed. W. H. Freeman, 2016. ISBN: 9781319145446.
| LEC # | TOPICS | READINGs FROM TEXTBOOK |
|---|---|---|
| 1 | Welcome; Introduction and course organization | |
| 2 | Chemical bonding and molecular interactions; Lipids and membranes |
Chapter 2: Sections 2.1–2.4 Chapter 3: Sections 3.1 & 3.4 Chapter 6: Section 6.1 |
| 3 | Structures of amino acids, peptides and proteins | Chapter 3: Section 3.2 |
| 4 | Enzymes and metabolism | Chapter 8: Sections 8.1–8.5 (plus Ch. 8 recap) |
| 5 | Carbohydrates and glycoproteins | Chapter 3: Section 3.3 |
| 6 | Nucleic acids |
Chapter 4: Sections 4.1 & 4.4 Chapter 13: Sections 13.1–13.2 |
| 7 | Replication | Chapter 13: Sections 13.3–13.4 (plus Ch. 13 recap) |
| 8 | Transcription | Chapter 14: Sections 14.1–14.3 |
| 9 | Chromatin remodeling and splicing | Chapter 14: Section 14.4 |
| 10 | Translation | Chapter 14: Section 14.5 (plus Ch. 14 recap) |
| 11 | Cells, the simplest functional units | Chapter 5: Sections 5.1–5.3 |
| 12 | Genetics 1—Cell division and segregating genetic material | Chapter 11: Sections 11.1 & 11.3–11.5 |
| 13 | Genetics 2—Rules of inheritance | Chapter 12: Section 12.1 |
| 14 | Genetics 3—Linkage, crossing over | Chapter 12: Sections 12.4 & 12.5 |
| 15 | Genetics 4—The power of model organisms in biological discovery | Chapter 12: Sections 12.4 & 12.5 |
| 16 | Recombinant DNA, cloning, and editing | Chapter 18: Sections 18.1–18.3 & 18.5–18.6 |
| 17 | Genomes and DNA sequencing |
Chapter 13: Section 13.5 Chapter 17: Sections 17.1–17.5 |
| 18 | SNPs and human genetics | Chapter 12: Section 12.2 |
| 19 | Cell trafficking and protein localization | Chapter 14: Section 14.6 |
| 20 | Cell signaling 1—Overview | Chapter 7: Sections 7.1–7.5 (plus recap) |
| 21 | Cell signaling 2—Examples | Chapter 7 continued |
| 22 | Neurons, action potential, and optogenetics |
Chapter 45: Sections 42.1–42.6 Chapter 46: Section 46.1 |
| 23 | Cell cycle and checkpoints | Chapter 11: Sections 11.1–11.5 |
| 24 | Stem cells, apoptosis, and tissue homeostasis |
Chapter 11: Section 11.6 Chapter 19: Sections 19.1 & 19.5 |
| 25 | Cancer 1 | Chapter 11: Section 11.7 |
| 26 | Cancer 2 | Chapter 11: Section 11.7 continued |
| 27 | Visualizing life—Dyes and stains | Chapter 5: Section 5.1 |
| 28 | Visualizing life—Fluorescent proteins | |
| 29 | Cell imaging techniques | |
| 30 | Immunology 1—Diversity, specificity, and B cells | Chapter 42: Sections 42.1–42.6 |
| 31 | Immunology 2—Memory, T cells, and autoimmunity | Chapter 42: Sections 42.1–42.6 |
| 32 | Infectious disease, viruses, and bacteria | |
| 33 | Bacteria and antibiotic resistance | |
| 34 | Viruses and anti-viral resistance | |
| 35 | Reproductive cloning and embryonic stem cells |
Chapter 11: Section 11.6 Chapter 19: Sections 19.1 & 19.5 |
| 36 | “In the news” |
