7.91J | Spring 2014 | Graduate

Foundations of Computational and Systems Biology

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Description:

Splice signal motifs of five species, created using the PICTOGRAM program. The height of each letter is proportional to the frequency of the corresponding base at the given position, and bases are listed in descending order of frequency from top to bottom. Courtesy of National Academy of Sciences. Source: Figure 2 of Lim, Lee P., and Christopher B. Burge. “A computational analysis of sequence features involved in recognition of short introns.” Proceedings of the National Academy of Sciences 98, no. 20 (2001): 11193-11198. Courtesy of National Academy of Sciences.

Alt text:
The letters A, T, G, and C, presented in different sizes and colors.
Caption:
Splice signal motifs of five species, created using the PICTOGRAM program. The height of each letter is proportional to the frequency of the corresponding base at the given position, and bases are listed in descending order of frequency from top to bottom. Source: Figure 2 of Lim, Lee P., and Christopher B. Burge. “A Computational Analysis of Sequence Features Involved in Recognition of Short Introns.” Proceedings of the National Academy of Sciences 98, no. 20 (2001): 11193–8. (Courtesy of National Academy of Sciences)
Credit:
Courtesy of National Academy of Sciences.
The letters A, T, G, and C, presented in different sizes and colors.
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