Foundations of Computational and Systems Biology

Video Lectures

Lecture 1: Introduction to Computational and Systems Biology

Lecture 2: Local Alignment (BLAST) and Statistics

Lecture 3: Global Alignment of Protein Sequences (NW, SW, PAM, BLOSUM)

Lecture 4: Comparative Genomic Analysis of Gene Regulation

Lecture 5: Library Complexity and Short Read Alignment (Mapping)

Lecture 6: Genome Assembly

Leture 7: ChIP-seq Analysis; DNA-protein Interactions

Lecture 8: RNA-sequence Analysis: Expression, Isoforms

Lecture 9: Modeling and Discovery of Sequence Motifs

Lecture 10: Markov and Hidden Markov Models of Genomic and Protein Features

Lecture 11: RNA Secondary Structure – Biological Functions and Prediction

Leture 12: Introduction to Protein Structure; Structure Comparison and Classification

Lecture 13: Predicting Protein Structure

Lecture 14: Predicting Protein Interactions

Lecture 15: Gene Regulatory Networks

Lecture 16: Protein Interaction Networks

Lecture 17: Logic Modeling of Cell Signaling Networks

Lecture 18: Analysis of Chromatin Structure

Lecture 19: Discovering Quantitative Trait Loci (QTLs)

Lecture 20: Human Genetics, SNPs, and Genome Wide Associate Studies

Lecture 21: Synthetic Biology: From Parts to Modules to Therapeutic Systems

Lecture 22: Causality, Natural Computing, and Engineering Genomes