Systems Biology

Lecture Videos

Introduction to the Class and Overview of Topics

Input Function, Michaelis-Menten kinetics, and Cooperativity

Autoregulation, Feedback and Bistability

Synthetic Biology and Stability Analysis in the Toggle Switch

Oscillatory Genetic Networks

Graph Properties of Transcription Networks

Feed-forward Loop Network Motif

Introduction to Stochastic Gene Expression

Causes and Consequences of Stochastic Gene Expression

Stochastic Modeling

Life at Low Reynolds Number

Robustness and Bacterial Chemotaxis

Robustness in Development and Pattern Formation

Microbial Evolution Experiments and Optimal Gene Circuit Design

Evolution in Finite Populations

Clonal Interference and the Distribution of Beneficial Mutations

Fitness Landscapes and Sequence Spaces

Evolutionary Games

Survival in Fluctuating Environments

Parasites, the Evolution of Virulence and Sex

Interspecies Interactions

Ecosystem Stability, Critical Transitions, and Biodiversity

Dynamics of Populations in Space

The Neutral Theory of Ecology