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Course Info

Instructor:
  • Prof. Jeff Gore
Course Number:
  • 8.591J
  • 7.81J
  • 7.32
Departments:
  • Physics
  • Biology
As Taught In: Fall 2014
Level: Graduate
Undergraduate

Topics

  • Engineering
    Biological Engineering
    Synthetic Biology
  • Science
    Biology
    Cell Biology
    Computation and Systems Biology
    Physics

Learning Resource Types

assignment Problem Sets
grading Exams
theaters Lecture Videos
co_present Instructor Insights
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Course Info
Systems Biology
  • Syllabus

  • Instructor Insights

    • Flipping the Classroom
    • Clickers or Flashcards?
    • Perceived Barriers to Active Learning
  • Readings

  • Pre-class Reading Questions

  • Lecture Videos

  • Assignments

  • Exams

Lecture Videos

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Introduction to the Class and Overview of Topics
Input Function, Michaelis-Menten kinetics, and Cooperativity
Autoregulation, Feedback and Bistability
Synthetic Biology and Stability Analysis in the Toggle Switch
Oscillatory Genetic Networks
Graph Properties of Transcription Networks
Feed-forward Loop Network Motif
Introduction to Stochastic Gene Expression
Causes and Consequences of Stochastic Gene Expression
Stochastic Modeling
Life at Low Reynolds Number
Robustness and Bacterial Chemotaxis
Robustness in Development and Pattern Formation
Microbial Evolution Experiments and Optimal Gene Circuit Design
Evolution in Finite Populations
Clonal Interference and the Distribution of Beneficial Mutations
Fitness Landscapes and Sequence Spaces
Evolutionary Games
Survival in Fluctuating Environments
Parasites, the Evolution of Virulence and Sex
Interspecies Interactions
Ecosystem Stability, Critical Transitions, and Biodiversity
Dynamics of Populations in Space
The Neutral Theory of Ecology

Course Info

Instructor:
  • Prof. Jeff Gore
Course Number:
  • 8.591J
  • 7.81J
  • 7.32
Departments:
  • Physics
  • Biology
As Taught In: Fall 2014
Level: Graduate
Undergraduate

Topics

  • Engineering
    Biological Engineering
    Synthetic Biology
  • Science
    Biology
    Cell Biology
    Computation and Systems Biology
    Physics

Learning Resource Types

assignment Problem Sets
grading Exams
theaters Lecture Videos
co_present Instructor Insights
MIT Open Learning
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