Laboratory Chemistry

A photograph of Dr. Dolhun standing at the chalkboard, wearing safety glasses and holding a small beaker containing a pale blue solution. There are two straws in the beaker.

What's in the beaker? What will happen next, and how does it relate to medicine, pH, and Cambridge's beloved Charles River? Watch Lecture 6 and find out! (Image by B. Paci, MIT OpenCourseWare).


MIT Course Number


As Taught In

Fall 2019



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Course Description

Course Features

Course Description

This course introduces experimental chemistry for students who are not majoring in chemistry. The course covers principles and applications of chemical laboratory techniques, including preparation and analysis of chemical materials, measurement of pH, gas and liquid chromatography, visible-ultraviolet spectrophotometry, infrared spectroscopy, nuclear magnetic resonance, mass spectrometry, polarimetry, X-ray diffraction, kinetics, data analysis, and organic synthesis.


Dr. Dolhun and Dr. Hewett would like to acknowledge the contributions of past instructors over the years to the development of this course and its materials.


The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented.

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John Dolhun, and Sarah Hewett. 5.310 Laboratory Chemistry. Fall 2019. Massachusetts Institute of Technology: MIT OpenCourseWare, License: Creative Commons BY-NC-SA.

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